蜂王浆咀嚼片增强免疫力功能实验研究  

Effects of Chewable Tablets of Royal Jelly on Strengthing Immunity Functions of Mice

作　　者：张红城[1,2] 董捷[1,2] 胡余明[3] 

机构地区：[1]中国农业科学院蜜蜂研究所,北京100093 [2]农业部国家蜂产品加工专业分中心,北京100093 [3]湖南省疾病预防控制中心,湖南长沙410005

出　　处：《食品科学》2008年第8期579-583,共5页Food Science

基　　金：农业部公益性行业(农业)科研专项经费项目(nyhyzx07-041);中国农业科学院蜜蜂研究所研发基金项目(200602);中国农业科学院蜜蜂研究所所长基金项目(200605)

摘　　要：为研究蜂王浆咀嚼片增强免疫力功能,经口给予小鼠0.167、0.333、0.999g/kg bw剂量的蜂王浆咀嚼片30d,结果表明0.333、0.999g/kg bw剂量能增强小鼠迟发型变态反应、提高小鼠的抗体生成细胞数,0.999g/kg bw剂量能增强小鼠单核-巨噬细胞碳廓清的能力及小鼠NK细胞活性。对小鼠体重增长、脾脏/体重比值、胸腺/体重比值、小鼠血清半数溶血值、ConA诱导的小鼠淋巴细胞转化能力和小鼠巨噬细胞吞噬鸡红细胞的能力无明显影响。表明蜂王浆咀嚼片具有增强免疫力的功能。In order to study effects of chewable tablets of royal jelly on immunity functions of mice, the mice were administered with the chewable tablets at the doses of 0.167, 0333 and 0.999 g/kg bw for 30 days by intragastric infusion, respectively. The results showed that the dose of 0.333 g/kg bw and 0.999 g/kg bw can strengthen the delayed type hypersensitivity of mice, and increased the quantity of antibody forming cells of mice. The dose of 0.999 g/kg bw can strengthen mononuclear macrophage carbon clearance and NK cells activity of mice, and has no significant effects on body weight increase, ratio of spleen weight to body weight, ratio of thymus weight to body weight, HC50, tlymphocyte transformation ability of mice induced by ConA and ability of chicken-red cells phagocytosis. So it is concluded that the chewable tablets of royal jelly can strengthen immunity functions of mice.

关 键 词：蜂王浆咀嚼片 增强 免疫力 

分 类 号：S896[农业科学—特种经济动物饲养]