乳腺癌术后两种镇痛方法的临床比较  

Clinical Comparison of Different Methods for Postoperative Analgesia after Mastectomy

作　　者：华丽[1] 王雄[1] 何斌[1] 魏江涛[1] 

机构地区：[1]成都铁路中心医院,四川成都610081

出　　处：《现代临床医学》2008年第4期279-280,共2页Journal of Modern Clinical Medicine

摘　　要：目的:比较乳腺癌术后两种镇痛方法的效果与不良反应。方法:将拟行择期乳癌根治术的60例病人随机分成罗哌卡因硬膜外镇痛组(PCEA组,n=30)和芬太尼静脉镇痛组(PCIA组,n=30)两组。PCEA组采用0.1%罗哌卡因(含芬太尼2μg.mL-1),PCIA组采用0.001%芬太尼加0.005%氟哌利多,比较观察术后镇痛镇静效果及不良反应。结果:术后镇痛效果两组比较无显著性差异(P>0.05),术后不良反应PCIA明显多于PCEA(P<0.05)。结论:用于乳癌术后镇痛0.1%罗哌卡因硬膜外镇痛优于芬太尼静脉镇痛。Objective： To compare the analgesic efficacy and side effects of different methods of analgesic alter mastectomy. Methods： Sixty ASA Ⅰ - Ⅱ patients undergoing radical operation for brest cancer were randomly divided into two groups： 0. 1% ropivacaine （containing fentanyl 2 μg·mL^-1） epidural analgesia （PCEA） group （ n = 30）. 0. 001% fentanyl with 0. 005 % droperidol controlled intravenous analgesia （PCIA） group （n = 30）. The postoperative analgesia efficacy and sedation efficacy and side- effects after operation were observed. Results： There was no obvious difference between the two groups about the effect of postoperative analgesia （ P 〉 0.05 ）. The side - effects were significantly more in group PCIA than those in group PCEA（P 〈0.05）. Conclusion： The method of epidural analgesia with 0. 1% ropivacaine is much better and more effective than the method of intravenous analgesia with fentanyl.

关 键 词：乳腺癌根治术 术后镇痛 芬太尼 罗哌卡因 

分 类 号：R737.9[医药卫生—肿瘤]