GC/MS定性K粉及其中间体的应用  

Application of intermediate product of ketamine by GC/MS

作　　者：高利娜[1] 刘俊亭[1] 杨卓[2] 

机构地区：[1]中国医科大学药物分析教研室,沈阳110001 [2]沈阳药科大学制药工程学院,沈阳110016

出　　处：《中国卫生检验杂志》2008年第8期1558-1558,1671,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:用GC/MS检测方法对氯胺酮的合成中间产物进行研究。方法:样品在碱性的条件下用乙酸乙酯萃取,GC/MS分析。结果:运用GC/MS确认了氯胺酮及其合成中间产物1-羟基环戊基邻氯苯基酮N-甲亚胺。结论:上述方法可以用于氯胺酮及其合成中间产物的测定。Objective： To study the intermediate product of ketamine by GC/MS.Methods：The specimens were alkalized and extracted with ethyl acetate,then analyzed by GC/MS.Results：Affirm ketamine and its intermediate product 1-hydrocyclopentyl-o-chlorophenyl ketone-N-methanimine were confirmed by GC/MS.Conclusion：This method could be used to determine the ketamine and its intermediate product.

关 键 词：氯胺酮 合成中间产物 GC/MS 

分 类 号：O657.63[理学—分析化学]