原发性颅内骨肿瘤的临床、光镜、电镜及免疫组化观察  

Primary Intracranial Bony Tumors:a Clinical,Light and Electron Microscopical and Immunohistochemical Study

作　　者：李南云[1] 严小娟[1] 钱源澄[1] 郑晓刚[1] 陆珍凤[1] 

机构地区：[1]南京军区南京总医院病理科,210002

出　　处：《江苏医药》1997年第11期761-763,共3页Jiangsu Medical Journal

摘　　要：颅内骨肿瘤为中枢神经系统（CNS）罕见肿瘤，本文报告6例，占我院2121例CNS肿瘤的0．28％。其中骨肉瘤成分为主的肿瘤、骨巨细胞瘤各1例，软骨肉瘤、骨软骨瘤各2例。患者年龄除2例外，均在28岁以下。骨巨细胞瘤病程最长，达10余年。所有肿瘤均在5cm以上，其中最大者为颅中凹骨软骨瘤，达9cm×7cm×7cm。骨肉瘤成分位于与颅骨无关的右颞顶叶脑实质内，极罕见。本组部分病例经电镜及免疫组织化学研究（GFAP、VIM、EMA、Keratin）证实肿瘤来源。Intracranial bony tumors are relatively rare tumors of the CNS. 6 cases were reported, representing0. 28% of a series of 2121 patients undergoing biopsy for CNS tumors. Tumors were mainly osteosarcoma 1, os-teogenic giant cell tumor 1, chondrosarcomas 2 and osteochondrornas 2. All these 6 cases were studied. The age of4 patients was under 28 years. The course of the patient with osteogenic giant cell tumor was the longest, for tenyears and more. All the tumors were over 5 cm in diameter. osteochondroma lccated in the middle fbesa was thegreatest, measuring 9. 0cm×7. 0cm×7.0cm. It was extremely rare that osteosarcorna component happened tooccur in the temporoparietal lobe without affection to the skull. The origin of tumors could be demonstrated byelectron microscopy and immunohistochemical examination. The clinical, Patbological features and origin of fourkinds of tumors were discussed.

关 键 词：颅内肿瘤 颅内骨肿瘤 光镜 电镜 免疫组织化学 

分 类 号：R739.41[医药卫生—肿瘤] R738.1[医药卫生—临床医学]