内镜智能分光比色与染色技术对诊断大肠肿瘤性病变的临床研究  

A Study of Fuji Intelligent Chromo Endoscopy and Chromoendoscopy in The Diagnosis of Colonrectal Neoplasia

作　　者：徐宁[1] 黄留业[1] 刘运祥[1] 吴承荣[1] 崔俊[1] 宋波[1] 衣龙志[1] 

机构地区：[1]青岛大学医学院附属烟台毓璜顶医院消化科,264000

出　　处：《中国消化内镜》2008年第5期19-22,共4页Digestive Disease and Endoscopy

基　　金：山东省自然科学基金资助项目(Y2007C120)

摘　　要：目的探讨内镜智能分光比色技术(FICE)在诊断大肠肿瘤性病变的价值。方法选择2007.8～2008.3间共581例患者进行常规内镜检查,其中发现大肠新生物或息肉样病变者共197例入选。分别采用常规放大技术、FICE放大技术及染色放大技术对病变进行腺管开口分型及毛细血管形态观察,对病变作出诊断,并与病理组织学诊断相比较。结果在197例病人中发现新生性病变398个,其中常规放大内镜下发现病变361个(90.8%),FICE放大模式下发现病变393个(98.7%)。FICE放大内镜比染色放大内镜更能清晰显示粘膜毛细血管结构形态(P<0.05),在显示腺管开口方面两者无统计学意义。FICE放大内镜对肿瘤性及非肿瘤性判断符合率为91.3%(359/398),高于染色放大内镜82.4%(328/398)(P<0.05)。结论FICE放大内镜可以观察粘膜表面微细结构及毛细血管形态,对大肠肿瘤性及非肿瘤性病变诊断的符合率高于普通放大内镜及染色放大内镜,特别有利于发现平坦型病变,有良好的临床应用价值。Objective： To investgate the value of Fuji Intelligent Chromo Endoscopy （FICE） for the diagnosis ofcolonrectal neoplasia. Methods： 581 patients were examined with ordinary colonoscopy from August in 2007 to March in 2008. 197 patients with colon neoplasm or polypoid lesion were enrolled in this study. The patients were examined with magnifying conventional colonoscopy, magnifying FICE technique and magnifying chromoendoscopy technique, the pit pattern and blood capillary form of the lesion were examined.The endoscopic diagnosis was made, and compared with pathologic diagnosis. Results： 398 neoplasms were detected in the 197 patients, among those 90.8%（361/398） were detected with magnifying conventional endoscopy, 98.7%（393/398） were detected with FICE technique, there was significant difference between the two methods. FICE could more clearly show the structure and form of mucosal blood capillary than chromoendoscopy technique, （P〈0.05）, there was no significant difference between the two methods for showing the pit pattern. The coincident rate ofFICE for the diagnosis of tumor and non-tumor lesions was 91.3%（359/398）, which was significant higher than that of chromoendoscopy 82.0%（328/398）（P〈0.05）. Conclusions： Magnifying FICE endoscopy could show mucosal microstructure and blood capillary form.It had the superiority of high coincident rate in distinguishing neoplastic from non-neoplastic colorectal lesions compared with conventional magnifying colonoscopy and magnifying chromoendoscopy. The detected rate of flat neoplasm was dramatically increased with FICE. FICE could be easily operated, and had satisfactory clinical practical value.

关 键 词：智能分光比色技术 大肠肿瘤 诊断 

分 类 号：R735.34[医药卫生—肿瘤] R737.9[医药卫生—临床医学]