交让木属植物中生物碱类化合物的研究进展  

Recent Research Progresses on Alkaloids from Genus Daphniphyllum

作　　者：王奎武[1] 张虹[1] 沈莲清[1] 

机构地区：[1]浙江工商大学食品与生物工程学院,浙江杭州310035

出　　处：《林产化学与工业》2008年第4期123-130,共8页Chemistry and Industry of Forest Products

基　　金：浙江省"食品科学重中之重"开放课题(无编号);浙江工商大学引进人才科研启动费(无编号)

摘　　要：生物碱广泛存在于自然界,是科学家们研究最早的一类有生物活性的天然有机化合物。随着植化分离和结构鉴定手段的提高,越来越多的生物碱类化合物被从交让木属植物中分离鉴定出来,近年来已鉴定80余种化合物。为了更好地开发和利用本属植物,作者在查阅国内外文献的基础上就这一领域的研究进展进行了综述。Alkaloids are natural organic compounds that were the most early studied by scientists and most of them have good bioactivities. Plants of the genus Daphniphyllum are known to metabolize structurally diversified Daphniphyllum alkaloids with highly complex polycyclic skeleton. Daphniphyllum alkaloids have been the challenging subjects in biogenetic and synthetic programs of natural products. Some of these alkaloids exhibited cytotoxic activities against several tumor cell lines. Along with the developments of isolation and structure elucidation techniques of phytocbemistry, more and more compounds of this genus were isolated and identified. More than 70 compounds were obtained from this genus of plants in recent research. In order to assist the medicinal application of this genus of plants, progresses made in this field were systemically reviewed, which will be benefitial for further research and development of these compounds.

关 键 词：交让木属 化学成分 生物碱 

分 类 号：TQ91[化学工程] O629.3[理学—有机化学]