310例肺癌骨转移患者核素全身骨显像分析  

Assessment of radionuclide scanning in 310 pulmonary carcinoma patients with bone metastasis

作　　者：张珂[1] 孔祥辉[1] 吴志兴[1] 吕宽[1] 申超[1] 刘春雨[1] 刘家林[2] 

机构地区：[1]山东大学附属省立医院核医学科,山东济南250021 [2]济南锅炉集团公司职工医院,山东济南250023

出　　处：《中国临床医学影像杂志》2008年第8期570-572,共3页Journal of China Clinic Medical Imaging

摘　　要：目的:探讨肺癌骨转移患者图像特点及规律。方法:使用SPECT双探头仪对310例肺癌患者进行核素全身骨显像,必要时加做局部静态显像。结果:①肺癌骨转移患者中,腺癌阳性率最高(64.83%);②肋骨为最多见转移部位(263例);③多发转移病灶250例,占80.6%,单发转移病灶60例,占19.3%。结论:放射性核素全身骨显像能较X线、CT提前3～6个月发现骨转移病灶,是目前临床上诊断骨转移的首选检测方法;周围型肺癌患者骨转移发生率高于中央型肺癌患者;对于不典型的异常病灶应通过补充X线摄片、CT检查最终明确诊断;骨显像异常病灶的数目与患者的预后相关。Objective To evaluate the characteristics of radionuclide bone imaging in pulmonary carcinoma patients with bone metastasis. Methods： Radionuclide bone scan by double gantre SPECT were performed in 310 pulmonary carcinoma patients with bone metastasis, and local imaging were performed when necessary. Results： The bone metastasis is most common in patients with adenocarcinoma of lung（64.83%）. Most metastatic foci were seen in bones of the rib（263 cases）. Multiple abnormal radionuclide concentration were seen in 250 patients （80.6%）, and 60 patients with only one foci （19.3%）. Conclusion： The bone metastasis could be detected 3-6 months earlier using radionuclide bone scan, which is the method of choice for diagnosing bone metastasis, other than X-ray and CT. The incidence of bone metastasis in peripheral lung cancer is higher than in central lung cancer, which suggests that the bone metastasis is associated with the primary site of the cancer and the onset time of clinical symptoms. And the prognosis of the patient is related to the number of bone metastatic foci in radionuclide bone imaging.

关 键 词：肺肿瘤 肿瘤转移 放射性核素显像 

分 类 号：R734.2[医药卫生—肿瘤] R73-37[医药卫生—临床医学]