小儿胃幽门螺杆菌感染诊断方法的研究  

A study on diagnostic methods for Helicobacter pylori infections in children

作　　者：袁梅侠[1] 沈柏均[1] 钟传植 侯怀水[1] 马玉燕[1] 

机构地区：[1]山东医科大学附属医院儿科

出　　处：《中华儿科杂志》1997年第12期639-640,共2页Chinese Journal of Pediatrics

摘　　要：为探讨小儿幽门螺杆菌（ＨＰ）感染诊断的最佳手段，对９８例不同群体小儿用胃粘膜活检标本尿素酶快速诊断法、血清ＨＰ－ＩｇＧ测定法、胃液ＨＰ－聚合酶链反应（ＰＣＲ）法进行了ＨＰ感染的对比性研究。结果：三种方法在上消化道疾病组胃粘膜活检标本中ＨＰ感染阳性率分别为４２％、５４％、４８％，与非消化道疾病及健康小儿对照组差异有显著性意义（Ｐ＜０．００５）。结果表明：三种方法在检测ＨＰ的阳性率方面无明显差别，而胃液ＨＰ－ＰＣＲ法方法简单实用、敏感性和特异性均较好，可作为诊断ＨＰ感染的最佳方法之一。To search for the best diagnostic approach to Helicobacter pylori (HP) infection in children. The authors conducted a comparative study on gastric mucosa′s urease test, serum HPIgG antibody and gastric juice HPPCR in 98 children. The results showed that in the cases with upper gastrointestinal (GI) tract diseases, the urease test, HPIgG and HPPCR were positive in 42%、 54% and 48%, respectively. The difference among the groups with upper GI tract disorders, nonupper GI tract disorders and the healthy children was significant. Of the 3 diagnostic methods, HPPCR was found a simpler, more sensitive, and more practical one.

关 键 词：螺杆菌感染 胃镜检查 诊断 

分 类 号：R573.104[医药卫生—消化系统]