乳腺癌雌激素和黄体酮受体的检测  

ESTROGEN AND PROGESTERONE RECEPTORS IN BREAST CANCER

作　　者：肖志强[1] 胡有秋[1] 费慧娟[2] 

机构地区：[1]湖南医科大学肿瘤研究所 [2]湖南医科大学第一附属医院外科

出　　处：《湖南医科大学学报》1990年第2期123-126,共4页Bulletin of Hunan Medical University

基　　金：湖南省卫生厅资助课题

摘　　要：用链霉亲和素—生物素—辣根过氧化酶配体免疫组化法,在84例乳癌石蜡切片上进行雌激素受体(ER)和黄体酮受体(PR)检测,ER、PR阳性分别为46和54例,与文献报道一致,其中ER(+)/PR(+)40例、ER(+)/PR(-)6例、ER(-)/PR(+)14例、ER(-)/PR(-)23例;ER和PR的表达与乳癌组织学类型和分化程度密切相关,与患者的年龄、月经状态无明显相关。The immunoc ytochemical method established by our institute was used to detect estrogen receptor (ER) and progesterone receptor(PR)on paraffin embedded sections of 84 breast cancer specimens. Results indicated: (1) of 84 specimens. 46 was ER positive and 54 was PR positive. (2) the relationship of ER and PR expression was as follows: ER(+)/PR(+) in 40 ER(+)/PR(-) in 6, ER(-)/PR (+) in 14. and ER(-)/PR(-) in 23 patients. (3)ER and PR expression were significantely correlated with the histological classification and differentiation of the cancer. (4) and no significante correlation with the age or menopausal status.

关 键 词：乳腺癌 雌激素 黄体酮 受体 

分 类 号：R737.903[医药卫生—肿瘤]