垂体后叶素治疗肝硬化食管静脉曲张大出血的近期疗效观察  

TREATMENT OF VASOPRESSIN IN PATIENTS WITH ESOPHAGEAL VARICEAL HEMORRHAGE

作　　者：唐丽安[1] 张桂英[1] 凌奇荷[1] 

机构地区：[1]湖南医科大学第一附属医院内科

出　　处：《湖南医科大学学报》1990年第3期277-278,288,共3页Bulletin of Hunan Medical University

摘　　要：肝硬化食管静脉曲张破裂大出血25例进行大剂量垂体后叶素(0.1～0.4u/min)连续静脉滴注及甲氰咪胍静脉注射。近期疗效观察表明,有效率80％、死亡率12％。并用扩张血管药物对原有心血管疾患或老年患者可缓解垂体后叶素的副作用,达到较好的止血疗效。Twenty-five patients with large amoont of acute bleeding from esophageal varicose veins were treated with either continuous intravenous infusion of 0.1 -0.4u/min vasopressin (VP ) and cimetidine from 1985 to 1987 in our hospital. The results were compared with that of 20 patients who were treated with 10-20μ/24h VP from 1982 to 1984 (?)The total effective hemostatic rate and the motality rate were 80%, 45% (P<0.05) and 12%, 55% (P<0.01) respectively. On the other hand in combination with vasodilator , they can be administered to vaso-circulatory disease patients who are over the age of 50 .

关 键 词：肝硬变 食管静脉曲张 垂体后叶素 

分 类 号：R571.305[医药卫生—消化系统]