探讨奥曲肽治疗急性肝硬化并食管-胃底静脉曲张破裂出血的疗效  

Inrestigate the Octreotide effect Oesophagus-fundus of stomach varicosity to massivehemorrhage

作　　者：张志萍[1] 

机构地区：[1]湖南省津市监狱医院,415400

出　　处：《中国现代药物应用》2008年第17期40-41,共2页Chinese Journal of Modern Drug Application

摘　　要：目的探讨奥曲肽治疗肝硬化并食管-胃底静脉曲张破裂出血引起急性上消化道出血的疗效。方法对43例肝硬化并食管-胃底静脉曲张破裂出血(EV)患者,观察应用奥曲肽后24h止血情况。结果所有患者24h止血率为88.4%,治疗过程均未见毒副反应。结论本实验表明奥曲肽治疗肝硬化并食管-胃底静脉曲张破裂出血的急性上消化道出血疗效显著,安全可靠,在急救过程中可考虑优先选用。Objective To investigate effect of bleeding contro with Octreotide in acute hepatocirrhosis with oesophagus-fundus of stomachvaricosity to massive hemorrhage. Methods The effect of bleeding control in the pa- tients of massive upper gastrointestinal hemor-rhage was evaluated after Octreotide used for 24 hours. 43 patients of hepatocirrhosis with oesophagus-fundus of stomachvaricosity bleeding were involved in the clinical research. Results The rate of bleeding control within 24 hours in all patients was 88. 4%. Toxic and side effect was not observed in the course of treatment. Conclusion Octreotide was effective and safe hemostatic and it can be used preferentially in the first aids of acute hepatocirrhosis with eesophagus-fundus of stomach varicosity hemorrhage.

关 键 词：奥曲肽 肝硬化 食管-胃底静脉曲张 出血 

分 类 号：R575.2[医药卫生—消化系统]