苯乙醛和对甲氧基苯甲醛的新合成方法  

A Novel Synthetic Method for Phenylacetaldehyde and p-Methoxybenzaldehyde

作　　者：岳可芬[1] 周春生[2] 姜严梅[1] 

机构地区：[1]西北大学合成与天然功能分子化学教育部重点实验室西北大学化学系,西安710069 [2]商洛师范学院化学系

出　　处：《应用化学》2008年第9期1113-1115,共3页Chinese Journal of Applied Chemistry

基　　金：西北大学基金(02NW15)资助项目

摘　　要：分别以苯乙酸和对甲氧基苯甲酸为原料,与邻苯二胺、碘甲烷经环化、季铵化反应简便合成1,3-二甲基-2-取代苯并咪唑盐,相应苯并咪唑盐与碲氢化钠经还原-水解反应分别制得苯乙醛和对甲氧基苯甲醛。并对苯并咪唑盐与碲氢化钠的还原-水解反应机理进行了讨论。1,3-Dimethyl-2-substituted benzimidazolium salts can be easily prepared from phenylacetate or p-methoxybenzoic acid, o-phenylenediamine and methyl iodide via cyclization and quarternarization. Phenylacetaldehyde and p-methoxylbenzaldehyde were respectively prepared through the reduction-hydrolysis reaction of the corresponding 1,3-dimethyl-2-substituted benzimidazolium ioidide with sodium hydrogen telluride. A novel synthetic method for phenylacetaldehyde or p-methoxylbenzaldehyde from phenylacetate or p-methoxybenzoic acid via reduction-hydrolysis of benzimidazolium salt is presented. This synthetic route has mild reaction conditions and high product purities. The reaction mechanism is discussed.

关 键 词：苯乙醛 对甲氧基苯甲醛 二甲基取代苯并咪唑盐 碲氢化钠 

分 类 号：O625[理学—有机化学]