海南粗榧中的木脂素及其抗氧化活性  

Antioxidant Lignans from Cephalotaxus hainanensis

作　　者：刘胜兰[1] 曾艳波[1] 韩壮[1] 梅文莉[1] 戴好富[1] 

机构地区：[1]中国热带农业科学院热带生物技术研究所,海南海口571101

出　　处：《河南大学学报（医学版）》2008年第3期29-31,共3页Journal of Henan University:Medical Science

基　　金：国家自然科学基金项目(30560018);973计划前期研究专项(2007CB116306)

摘　　要：目的:对海南粗榧化学成分进行分离鉴定。方法:采用反复柱色谱方法进行分离,通过理化性质和波谱分析鉴定结构,应用DPPH法测定化合物的抗氧化活性。结果:从海南粗榧的乙醇提取物中分离得到2个木脂素类化合物,经波谱鉴定分别为(+)-Matairesinol(1)和(+)-Isolariciresinol 3a-O-β-D-glucopyranoside(2)。结论:化合物1和2均为首次从该属植物中分离得到,活性测试结果表明上述两个化合物均具有抗氧化活性。Objective： To determine the extraction of the chemical constituents from Cephalotaxus hainanensis Li. Methods： The constituents were isolated and purified by column chromatography, and their structures were identified by physiochemical and spectral data. Antioxidant activity of the isolated compounds was tested by DPPH method. Results： Two lignans were isolated from the ethanol extract of Cephalotaxus hainanensis IA., and their structures were elucidated as （ ＋ ）-Matairesinol （1） and （ ＋ ）-Isolariciresinol 3a-O-β-D- glucopyranoside （2）. Conclusion： Compounds 1 and 2 are isolated from the genus of Cephalotaxus for the first time, and both of them show antioxidant activity.

关 键 词：海南粗榧 木脂素 DPPH 抗氧化活性 

分 类 号：R284.1[医药卫生—中药学]