洁厕精致腐蚀性胃炎实验和治疗  

Empirical study and treatment analysis of corrosive gastritis by toilet cleaner

作　　者：张汝钢[1] 闫秀英[1] 郭先科[1] 

机构地区：[1]中国人民解放军第150中心医院消化内科,河南省洛阳市471031

出　　处：《中华急诊医学杂志》2008年第8期852-854,共3页Chinese Journal of Emergency Medicine

摘　　要：目的探讨酸性洗涤剂洁厕精对消化道黏膜的损害及治疗方法。方法采用动物实验研究洁厕精对大白兔的急性毒性，对误服洁厕精患者观察其对消化道黏膜的亚急性和慢性毒性并探讨治疗方法。结果经口腔灌注洁厕精15ml，大白兔均于2h内死于胃穿孔；患者误服洁厕精50ml，经相关治疗7d，胃镜检查提示腐蚀性胃体溃疡，治疗14d，上消化道钡餐检查提示胃窦部缩窄炎症，治疗51d，胃镜检查提示胃体胃窦溃疡疤痕形成。结论酸性洗涤剂主要损害胃黏膜，急性期易致胃穿孔，亚急性期引起胃溃疡形成，慢性期引起瘢痕形成；治疗上，以口服纯牛奶、抑酸、止血为主；亚急性和瘢痕形成期均可以进行胃镜和上消化钡餐检查。Objective To study the gastrointestinal tract damage induced by acid detergent toilet cleaner and treatment methods. Method Acute toxicity of toilet cleaner was studied using big white rabbits. Subacute and chronic toxicity and treatment methods were studied by hospital patients. Results After filling 15 ml toilet cleaner into stomach through mouth in 2 rabbits, both died of gastric perforation. After one patient misapplied with 50 ml toilet cleaner, gastric corrosive ulcer was found by gastroscopy after treatment 7 d, gastric constrictive inflammation was found by upper gastrointestinal barium meal at 14 d after treatment, and gastric scarring was found by gastroscopy after treatment 51 d. Conclusions Acid detergent toilet cleaner mainly harm gastric mucosa, gastric perforation is easily induced in acute stage, gastric ulcer induced in subacute stage, and scarring induced in chronic stage. Taking orally pure milk, inhibiting gastric acid secretion and haemostasis are mainly treatment methods. Examination of gastroscopy and upper gastrointestinal barium meal may be carried out in subacute and chronic stages.

关 键 词：酸性洗涤剂 洁厕精 腐蚀性胃炎 治疗 

分 类 号：R573.3[医药卫生—消化系统]