射频消融治疗5cm以下老年性肝癌的临床研究  

Radiofrequency ablation in the treatment of live cancer which diameter is 5cm or less (≥60 years old)

作　　者：许若才[1] 李建良[1] 刘寒春[1] 余智渊[1] 孔轶[1] 马国安[1] 李科[1] 欧双艳[1] 

机构地区：[1]湖南省肿瘤医院介入治疗中心,湖南省肿瘤医院内科,长沙市410013

出　　处：《微创医学》2008年第5期419-421,共3页Journal of Minimally Invasive Medicine

基　　金：湖南省科委科技基金赞助项目(基金编号:06JT3006)

摘　　要：目的总结射频消融(RFA)治疗首诊直径≤5cm老年性肝癌的疗效和经验。方法1999年9月至2006年12月,采用徒手单人操作技术,多针、多点RFA治疗的方法治疗直径≤5cm老年性肝癌33例,力争瘤体完全凝固。结果33例36个结节共行144点RFA,每个结节行4点RFA治疗,无1例严重并发症发生;肿瘤完全凝固率93.9%(31/33),AFP转阴率75.0%(9/12);1、3、5年转移复发率分别为15.2%、51.6%、60.6%,1、3、5年生存率分别是96.9%、66.0%、32.4%。结论RFA治疗直径≤5cm老年性肝癌,安全微创,疗效显著,可成为首选治疗方法之一。Objective To study the effect of radiofrequency ablation（RFA） in the treatment of first diagngstic live cancer which diameter is 5cm or less （≥60 years old） and summarize experience. Methods For the purpose of complete coagulation and radical ablation,33 cases of live cancer （ ≤5cm, ≥60 years old） underwent RFA in our hospital from Sep 1999 to Dec 2006 with alone bare-handed,multi-needle and multi-point RFA. Results 36 tumors of 33 cases received 144 points RFA ,each tumor underwent 4-point RFA, and no one had serious complications. The rate of tumor complete coagulation was 93.9% （31/33） , the rate of AFP from positive to negative was 75.0% （9/12） ,the rate of recurrence of 1,3,5-year was 15.2%, 51.6% and 60.6%, the rate of 1,3,5 year survival was 96.9% ,66.0% and 32.4% with Kaplan-Meier. Conclusion It is safe to use RFA to cure the live cancer （ ≤5cm,≥60 years old）, and the method is micro-wound. Totally, the effect is obvious. RFA is one of the first choices for live cancer＇s treatment.

关 键 词：肝肿瘤 老年人 射频消融 

分 类 号：R735.7[医药卫生—肿瘤]