低浓度一氧化碳对人体生理功能的影响  

Effects of Low Concentration Carbon Monoxide on Human Physiological Function.

作　　者：余秉良[1] 张恒太[1] 牟晓非[1] 于芳[1] 钟浩[1] 何正杰[1] 

机构地区：[1]航天医学工程研究所

出　　处：《航天医学与医学工程》1997年第5期328-332,共5页Space Medicine & Medical Engineering

摘　　要：在模拟密闭环境的模拟舱内研究了低浓度ＣＯ对人体生理功能的影响。在３５ｍｇ／ｍ３浓度下，受试者出现轻度感觉症状、对比视力下降、心电Ｔ波降低和操作工效下降。在８０ｍｇ／ｍ３和１１５ｍｇ／ｍ３浓度下，上述变化更加明显且出现高频听阈升高。结果表明，低浓度ＣＯ对中枢神经系统和心脏功能有抑制性影响。依据人体ＣＯ吸收曲线，以ＣＯＨｂ饱和度为指标，得到ＣＯ感觉效应水平和视觉效应水平为７％；听觉效应水平为９％。Human volunteers were exposed to various low concentrations of carbon monoxide(CO) in a closed cabin.The results showed that 35mg/m 3 of CO caused slight subjective symptoms and reduction in contrast vision,operating efficiency and T-wave of ECG .At 80mg/m 3 and 115mg/m 3 the above changes were more severe and a rise in hearing threshold level was observed.It demonstrated that an inhibitory effect on the CNS and heart were caused by low concentrations of CO.According to the absorption curves for human exposed to CO,it is suggested that the sense effect level and vision effect level for CO are 7%COHb,and the hearing effect level is 9%COHb.

关 键 词：一氧化碳 生理影响 毒性 碳氧血红蛋白 座舱 

分 类 号：R852.17[医药卫生—航空、航天与航海医学]