急性脑梗死患者脑微栓子与颈动脉硬化的关系  

The relationship of MES and carotid arteriosclerosis in patients with cerebral infarction

作　　者：徐丽君[1] 周玉珍[1] 王春芝[1] 丁勇民[1] 

机构地区：[1]南昌大学第二附属医院神经内科,江西南昌330006

出　　处：《中风与神经疾病杂志》2008年第4期453-455,共3页Journal of Apoplexy and Nervous Diseases

摘　　要：目的探讨急性脑梗死患者脑动脉系统微栓子(MES)与颈动脉硬化的关系。方法收集急性脑梗死患者73例,进行脑动脉微栓子监测和颈动脉彩色多普勒超声检测,观察有脑动脉系统微栓子的病例数。结果(1)41例有颈动脉斑块,32例无颈动脉斑块;(2)有颈动脉斑块者MES阳性率(46.34%)较无斑块者MES阳性率(21.88%)高(P<0.05);(3)颈动脉不稳定斑块MES阳性率(80%)较稳定性斑块MES阳性率(26.92%)高(P<0.01);(4)MES与颈动脉的狭窄程度、内膜增厚及斑块的个数无相关性。结论颈动脉粥样硬化斑块的存在及不稳定性是导致脑动脉系统微栓子的重要因素之一,应高度重视,稳定颈动脉斑块是防治动脉至动脉栓塞的重要措施。Objective To determine the relationship of carotid atherosclerosis and microembolic signal（MES） in patients with cerebral infarction. Methods 73 patients with acute cerebral infarction were recruited. The cerebral artery MES were monitored by TCD, and the carotid atherosclerosis were detected by color transcranial Doppler. The cases with cerebral artery MES were recorded. Results There were 41 patients with carotid atherosclerotic plaque, and 32 patients without. The presence of MES in patients with carotid plaques （46.34%） was significantly higher than patients without carotid plaques （21.88% ） （ P 〈 0.05）. The presence of MES in patients with unstable carotid plaques （ 80% ） was significantly increased than patients with stable carotid plaques（26.92% ）（P 〈0.01 ）. The presence of MES hadn＇t any relationship with the degree of carotid stenoses,inner membrane＇s thickness and quantity of the carotid plaque. Conclusion The presence and instability of carotid plaque are main factors for carotid atherosclerosis resulting cerebral infarction. It should be highly valued that the stabilization of carotid plaque is an important measure to prevent artery and artery embolism.

关 键 词：微栓子 颈动脉硬化 脑梗死 

分 类 号：R743.3[医药卫生—神经病学与精神病学]