一氧化碳保护机制的研究进展  

Research progress of carbon monoxide protection mechanism

作　　者：马可[1] 徐鑫荣[2] 胡祖鹏[1] 

机构地区：[1]复旦大学附属华山医院急诊科,上海200014 [2]南京医科大学第一附属医院ICU,江苏南京210029

出　　处：《中国病理生理杂志》2008年第9期1865-1868,1872,共5页Chinese Journal of Pathophysiology

摘　　要：Carbon monoxide(CO) has been considered as a fatal gas.Recent researches show that tissues generate carbon monoxide,and carbon monoxide plays a key role in the tissue physiological and pathological processes.The endogenous CO is generated from the decomposition of heme which is catalyzed by heme oxygenase enzyme(HO).Studies show that CO involves in the process of anti-inflammation,anti-apoptosis,regulation of vascular tone,modulation of leukocyte adhesion and platelet aggregation.CO also functions as neurotransmitters.Carbon monoxide （CO） has been considered as a fatal gas. Recent researches show that tissues generate carbon monoxide, and carbon monoxide plays a key role in the tissue physiological and pathological processes. The endogenous CO is generated from the decomposition of heme which is catalyzed by heme oxygenase enzyme （HO）. Studies show that CO involves in the process of anti -inflammation, anti -apoptosis, regulation of vascular tone, modulation of leukocyte adhesion and platelet aggregation. CO also functions as neurotransmitters.

关 键 词：一氧化碳 血红素氧合酶 抗炎 抗细胞凋亡 白细胞黏附 血小板聚集 神经递质 

分 类 号：R363[医药卫生—病理学]