老年脑梗死患者部分危险因素的临床研究  

Clinical study of the risk factors of old cerebral infarction patient

作　　者：韩丽[1] 段俊丽[1] 潘志红[1] 顾祎[1] 陶蕊[1] 刘蓓菁[1] 

机构地区：[1]上海交通大学医学院附属新华医院老年科,200092

出　　处：《中国综合临床》2008年第10期1025-1028,共4页Clinical Medicine of China

摘　　要：目的探讨与老年脑梗死发病相关的因素。方法对2007年9—12月在我科佩戴过24h动态血压监测仪的205例〉65岁的老年男性患者的临床资料进行回顾性分析。按WHO脑梗死的诊断标准将患者分为两组：脑梗死组（58例）和非脑梗死组（147例），进一步分析各因素与脑梗死发病的相关性。结果①用多因素逐步Logistic回归分析（α=0．05，β=0．01为准入标准）得出：腔梗、血尿酸水平对脑梗死发病的影响作用具有显著性。其中腔梗患者对于非腔梗患者，脑梗死发病的相对危险度为7．443；血尿酸水平每减少1μmoL／L，脑梗死发病的相对危险度增加0.994。②血压各成分用两独立样本的￡检验分析得出：脑梗死组的收缩压最高值（167.12±22．08）mmHg、脉压最高值（88．03±20．81）mmHg，与非脑梗死组相比显著增高。结论对于老年男性人群，脑梗死的发病与是否患有腔梗、血尿酸水平有着显著关联；在血压成分中与收缩压最高值和脉压最高值关系非常密切。Objective To investigate the related risk factors of old cerebral infarction patient . Methods The related data of 248 old male patients（〉65） who weared the 24-h ambulatory blood pressure monitoring at our department from September of 2007 to December of 2007 were retrospectively analyzed. They were divided into two groups according to WHO diagnostic criteria for cerebral infarction：cerebral infarction group（n = 58） and non-cerebral infarction group（ n = 147 ）. The correlation between related risk factors with cerebral infarction were further studied. Results①The result of multiple factor logistic regression analysis （ α = 0.05,β = 0.01 is the selected criteri- on} showed ：cerebral lacunar infarction and the level of blood uric acid had the significant impact on the occurrence of cerebral infarction. To compare with non-cerebral lacunar infarction, the relative risk of cerebral infarction morbility was 7. 443 in cerebral lacunar infarction. The level of blood uric acid decreasing 1 μmol/L, the relative risk of cerebral infarction morbility increased 0.994 . ②Every ingredient of blood pressure deploy independent-samples T test showed that the highest value of systolic blood pressure （ 167.12 ± 22.08 ） and the highest value of pulse pressure （88.03 ± 20.81 ） raised up obviously compared with non-cerebral infarction group. Conclusion In old male, the incidence rate of cerebral infarction is predominantly correlated with cerebral lacunar infarction and the level of blood uric acid, and is closely correlated with the highest value of systolic blood pressure and the highest value of pulse pressure in all the ingredients of blood pressure.

关 键 词：脑梗死 老年人 血尿酸 

分 类 号：R743.33[医药卫生—神经病学与精神病学]