林州市413个食管癌高发村产生的原因及预防措施探讨  

The causes and preventive measures in LinZhou 413 villages having a high incidence of esophageal cancer

作　　者：韩建英[1] 徐致祥[2] 邢海平[1] 谭家驹[2] 王民宪[1] 孔芳君[1] 张栓虎[1] 李笑梅[1] 李金辉[1] 郭鹏飞[1] 

机构地区：[1]安阳市疾病预防控制中心,河南安阳455000 [2]佛山市第一人民医院,广东佛山528000

出　　处：《河南预防医学杂志》2008年第5期321-323,共3页Henan Journal of Preventive Medicine

基　　金：广东省自然科学基金(04008530)(A1998646);安阳市社会发展攻关项目立项(编号:23号)

摘　　要：目的探讨安阳林州市产生413个食管癌高发村的原因及预防措施。方法制定统一调查表对林州市各村2001年-2003年饮用水类型、地形地貌、河流、各村人口数和食管癌发病、死亡数进行详细调查,食管癌资料没有包括贲门癌。结果林州市年平均气温12.8℃,年降水总量672.1 mm,属半干湿大陆性季风气候。17个乡个行政村资料完整,80%(428/534)的行政村有不同程度的食管癌发生,20%的没有食管癌发生。把食管癌死亡率16/10万以上村定为高发村,535个村中高发村413个占77.34%;在这413个村719 238人口中,山区丘陵人口数所占的比率越高,食管癌死亡率越高,成等级正相关,相关系数为1;其中有河流、灌溉渠的村272个,食管癌发病率106.93/10万、死亡率为100.82/10万,高于没有河流、灌溉渠的村59.03/10万、33.43/10万,差异有统计学意义;山区居民死亡率最高,山区死亡率94.38/10万>丘陵区76.29>平原区56.37/10万,成阶梯状递减;在食管癌死亡率16/10万以下的121个村中,平原区死亡率6.19/10万>丘陵区2.85>山区1.27/10万。结论干旱、半干旱气候区食管癌高发与大范围人群终生饮用低污染的河水、渠水、河边井水、山泉水有关,治理河流污染、远离河流打深水井,水质净化处理,可有效预防控制食管癌高发区的产生,氮循环致癌学说成立。Objective To explore the causes and preventive measures in 413 villages of LinZhou having a high incidence of esophageal cancer. Method It is statistical analysis between the three years survey data died of esophageal cancer of 534 villages, 719 238 people in 2001 -2003 to the terrain, rivers and other environmental information Results： In 534 survey villages, 80 percent of villages have varying degrees of esophageal cancer occurred. 413 villages that the mortality is more than 16/100 000 is 77.34 percent in 535 villages. The higher mortality rates of esophageal cancer, The larger rates of mountain counties people. The esophageal cancer mortality （ 100.82/10 0000 ） with rivers in the 413 villages is higher than the counties （ 33.43/100 000 ） away from the river and the differences were Significance. The mortality（ 94.38/100 000） in mountain villages is higher than counties （76.29/100 000） from mountain to Plain and is higher than Plain（56.37/100 000） , a ladder descending, The plain mortality （6.19/100 000） is higher than mountain （ 1.27/100 000 ） in 121 villages its esophageal cancer mortality rate is below 16/100 000. Conclusion The high incidence of esophageal cancer in semi - wet and dry climate is related that the large crowd drinking lower pollution water with lifetime as the river water, mountain spring water, governance river. It is effective to prevention and control of esophageal cancer with deep wells far away from a river, water purification,in a high incidence area.

关 键 词：食管癌高发村 林州市 肿瘤 

分 类 号：R735.1[医药卫生—肿瘤]