强化胃腔灌洗疗法治疗神经外科应激性溃疡出血100例  

A clinical analysis of intensive gastrointestinal lavage method for treatment of 100 severe cases with stress ulcer bleeding in neurosurgery department

作　　者：杨国平[1] 闵强[1] 韦君武[1] 

机构地区：[1]武汉市中西医结合医院神经外科ICU,湖北武汉430022

出　　处：《中国中西医结合急救杂志》2008年第5期304-305,共2页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

基　　金：湖北省武汉市医药卫生临床重点学科研究项目(武卫[2005]249)

摘　　要：目的探讨强化胃腔灌洗疗法对神经外科应激性溃疡出血的临床疗效。方法2005年7月- 2008年2月,应用强化胃腔灌洗疗法治疗本院神经外科重症加强治疗病房100例病情危重合并应激性溃疡出血患者,观察其疗效。结果100例患者中,成功止血97例,治疗有效率为97%;并发肺部感染死亡17例(占17%),应激性溃疡出血死亡3例(占3%),总病死率为20%。其余患者均治愈。结论强化胃腔灌洗疗法治疗应激性溃疡出血的临床疗效相当,可以通过减少胃内定植细菌来降低胃-肺感染途径所致的肺部感染率。Objective To discuss the intensive gastric cavitary lavage method in treatment of stress ulcer bleeding （SUB）. Methods The therapeutic effects of 100 patients with severe SUB in intensive care unit （ICU） from July 2005 to February 2008 treated with intensive gastric cavity lavage method were observed and analyzed. Results In these 100 cases, the bleeding was stopped successfully in 97 cases, the therapeutic effective rate being 97% there were 17 cases died of complicated pulmonary infection （17%） and 3 cases of bleeding （3%）, the total fatality rate being 20%. All the other cases were cured. Conclusion Intensive gastrointestinal lavage therapy is an effective method as acid inhibitor for treatment of SUB, but it can decrease the inhabitant flora in the stomach to pass through gastric-pulmonary route, thus the incidence of pulmonary infection was reduced.

关 键 词：胃腔灌洗 应激性溃疡出血 胃酸抑制剂 肺部感染 

分 类 号：R573.1[医药卫生—消化系统]