心肌靶心图定量分析病毒性心肌炎心肌微循环障碍的研究  

Evaluation of the myocardical microvascular damage in patients with viral myocarditis by myocardical Bull’s-eye

作　　者：程木华[1] 饶国辉[2] 周汉建[1] 许杰华[1] 

机构地区：[1]中山大学附属第三医院,广东广州510630 [2]中山大学附属第一医院,广东广州510089

出　　处：《中国热带医学》2008年第10期1766-1767,1769,共3页China Tropical Medicine

摘　　要：目的探讨心肌灌注显像中的靶心图定量分析技术,评价病毒性心肌炎心肌微循环受损情况。方法对58例临床诊断病毒性心肌炎患者及30例正常对照者,进行运动负荷和静息铊-201心肌灌注断层显像,常规图像重建后,对短轴心肌进行靶心图定量分析。结果58例病毒性心肌炎患者铊-201心肌灌注显像,靶心图异常有47例,呈"花斑状"特征,阳性率为81%。病毒心肌炎患者心肌缺血范围分数(ES)为(4.13±6.05),缺血严重分数(SS)是(123.07±69.03),与正常对照组的差异均有显著意义(P<0.01)。结论病毒性心肌炎患者大部分存在心肌微循环受损,靶心图定量分析是评价心肌炎心肌受累范围和程度的有效手段。Objective To analyse the change of myocardical microcirculation in patients with viral myocarditis with the bull＇s -eye quantitive technique of myoeardical perfusion imaging. Methods We had performed the stress and rest myocardical perfusion imaging with radioactive T1 -201 in 58 cases with viral myocarditis and 30 normal controls, then the acquisitive datum were reconstructed and the ischemia extent score and severity score were calculated by the bull＇ s - eye method. Results Myocardial Bull＇ s - eys showed there were 47 abnormal cases in 58 patients with viral myocarditis, the positive rate was 81%, and the abnormal characteristic was moiling shape. The myocardical ischemia extent score in patients was 4. 13 ±6.05, and the severity score was 123.07± 69.03, they were notablely higher than those in normal controls individually （P 〈 0.01 ）. Conclusion There were multifoeus of microvascular damage of myocardium in patients with viral myoearditis, the quantitive analysis with myocardical bull＇ s - eye was the effective method to evaluate the extent and severity of myocardical microvascular damage.

关 键 词：病毒性心肌炎 微循环 心肌灌注显像 靶心图 

分 类 号：R817.4[医药卫生—影像医学与核医学]