FLP-3型一步制粒机制备空白淀粉颗粒各项参数的控制研究  

Control and study on the various parameters of manufacturing blank starch granules with FLP-3 one-step-granulating

作　　者：魏玉梅[1] 

机构地区：[1]徐州医药高等职业学校,江苏徐州221116

出　　处：《齐鲁药事》2008年第8期495-496,共2页qilu pharmaceutical affairs

摘　　要：目的考察用FLP-3型一步制粒机制备空白淀粉颗粒时,不同的工艺参数对颗粒合格率的影响。方法采用单因素实验,以颗粒合格率为评价指标,对工艺参数进行考察。结果与结论最佳工艺参数为:引风大小要根据制粒物料状态不同随时进行调节,进风温度控制在90℃,雾化压力控制在0.1bar,喷雾速率由30rpm逐渐降低至20rpm。本研究可为用一步制粒机制备颗粒剂和教学提供参考。OBJECTIVE To investigate the different process parameters on the impact of granules passing rate, when manufacture blank starch granules with FLP- 3 one-step-granulating. METHODS Single factor experiment was adopted. Granules passing rate was used as evaluation criteria of the process parameters inspected. RESULTS AND CONCLUSION the best process parameters： with the wind according to the size granulation different materials at any time state to regulate. The into wind temperature was controlled at 90;. Atomization pressure was controlled in the 0. 1 bar. Spray rate was decreased from 30 rpm to 20 rpm. This study can be used to manufacture granules with FLP--3 one-step-granulating and practice teaching of vocational schools to provide information.

关 键 词：一步制粒 淀粉颗粒 工艺参数 合格率 

分 类 号：TQ460.5[化学工程—制药化工]