Prospect of Functional Salivary Gland Enhancement with Biomedical Strategies for Head and Neck Cancers  

作　　者：Suyu Zhu Bingqiang Hu Xiao Zhou 

机构地区：[1]Department of Radiation Oncology [2]Department of Oncologic Plastic Surgery-Head and Neck, the Hunan Province Cancer Hospital, Changsha 410013, Hunan Province, China.

出　　处：《Chinese Journal of Clinical Oncology》2008年第5期313-319,共7页中国肿瘤临床（英文版）

摘　　要：Xerostomia is the main complication inflicting head and neck cancer patients treated with radiotherapy.Conventional treatment is not very effective in alleviating this morbidity.Biomedical strategies such as gene transfer and tissue engineering have made substantial progress that will potentially lead to successful new treatment options for this condition.This report reviews the process of radiation damage to the salivary glands and the advances in functional salivary gland enhancement with these two brand-new technologies.Xerostomia is the main complication inflicting head and neck cancer patients treated with radiotherapy.Conventional treatment is not very effective in alleviating this morbidity.Biomedical strategies such as gene transfer and tissue engineering have made substantial progress that will potentially lead to successful new treatment options for this condition.This report reviews the process of radiation damage to the salivary glands and the advances in functional salivary gland enhancement with these two brand-new technologies.

关 键 词：XEROSTOMIA salivary gland radiation injury GENETHERAPY tissue engineering. 

分 类 号：Q691[生物学—生物物理学]