帕金森病交感神经皮肤电反应的初步探讨  

A primary study of sympathetic skin response in Parkinson＇s disease patients

作　　者：陈红霞[1] 于苏文[1] 祝育青 

机构地区：[1]解放军第102医院,江苏213003

出　　处：《常州实用医学》2008年第3期151-153,共3页CHANGZHOU PRACTICAL MEDICINE

摘　　要：目的探讨交感神经皮肤反应（SSR）对帕金森病（PD）患者自主神经功能障碍的诊断价值。方法对62例PD患者和35例健康人进行了SSR检测，并对比分析。结果PD患者SSR异常率为69％，SSR潜伏期明显延长，波幅明显降低，与正常对照组相比差异有显著性意义（P〈0．001）。结论PD患者存在一定的自主神经功能损害，SSR潜伏期和波幅的异常主要为中枢部位受损所致。SSR作为判断PD患者的自主神经功能障碍有一定临床意义。Objective To explore the value of sympathetic skin response in assessing the autonomic nerve dysfunction in patients with Parkinson disease. Methods sympathetic skin response （SSR）tests were performed for 62 PD patients and 35 healthy people.The results were compared between two groups. Results The abnormality rate of SSR in PD patients was 69%, the latency of SSR was longer and the amplitude of SSR was lower in PD patients than in the control group. There was significant difference between the two groups（ P 〈 0.001）. Conclusion PD patient＇s autonomic nerve function have a certain obstacle, The incubation period and amplitude of SSR are unusual mainly damaged for centre position, and is free of medication institute. SSR can be as the objective index of appraising PD patient＇s autonomic nerve function obstacle.

关 键 词：帕金森病 自主神经功能 交感神经皮肤反应 

分 类 号：R747.9[医药卫生—神经病学与精神病学] R742.5[医药卫生—临床医学]