Nd∶YAG耦合腔注入锁模激光脉冲列对兔眼损伤效应研究  

Study of damage effects of rabbit eyes induced by coupling cavity injection mode locked Nd∶YAG laser pulse train

作　　者：陈宗礼[1] 周淑英[1] 张桂素[1] 单清[1] 周铁球 徐碣敏 魏光辉[2] 李红[2] 

机构地区：[1]军事医学科学院放射医学研究所 [2]北京理工大学

出　　处：《激光技术》1997年第5期297-302,共6页Laser Technology

摘　　要：介绍Ｎｄ∶ＹＡＧ耦合腔自注入锁模基频皮秒激光脉冲列对兔眼的急性损伤效应，并与锁模倍频０５３μｍ激光及固体色心片锁模纳秒激光脉冲列损伤效应相比较。结果表明，锁模基频激光脉冲列兔眼急性损伤ＥＤ５０≈８３５μＪ，在损伤发生率为４０％时，基频和倍频平均角膜入射量分别为６２２μＪ和６１μＪ，比值为１０∶１，在损伤发生率为８３３％时，纳秒和皮秒基频脉冲列，平均角膜入射量分别为１１９０μＪ和２６０μＪ，比值为５∶１。A comparison of acute ocular damages of rabbit eyes induced by the coupling cavity injection mode locked Nd∶YAG laser picosecond pulse train and its doubled frequency 0.53μm pulse train and nanosecond pulse train using solid color centre crystal mode locked was reported.The result showed that the ocular damages(ED 50 ) was 83.5μJ at 1.06μm for mode locked picosecond laser pulse train;the energy required to produce lesions in 40% events was 62.2μJ at 1.06μm and 6.1μJ at 0.53μm,ratio 10∶1,and the dose required in 83.3% events,for nanosecond and picosecond laser pulse train,was 1190μJ and 260μJ at 1.06μm,ratio 5∶1 approximately.

关 键 词：眼损伤 耦合腔 注入锁模 激光脉冲列 锁模激光器 

分 类 号：R779.1[医药卫生—眼科] TN248.35[医药卫生—临床医学]