尿钾-肌酐比值对周期性瘫痪的早期诊断意义  

Value of Urine Potassium/Creatinine Ratio in Early Diagnosis of Hypokalemic Periodic Paralysis

作　　者：黄晓芸[1] 梅志忠[1] 罗进才[1] 

机构地区：[1]广东省东莞市厚街医院神经内科,523945

出　　处：《中华全科医学》2008年第10期1046-1047,共2页Chinese Journal of General Practice

摘　　要：目的探讨尿钾-肌酐比值对低钾型周期性瘫痪(HPP)的早期诊断意义。方法选择低钾型周期性瘫痪患者64例,根据病因分为原发组、继发组和甲亢组,健康志愿者25名作为对照组。测定血/尿钾浓度和肌酐,根据其结果计算尿钾-肌酐比值,比较组间差异。结果原发组尿钾-肌酐比值为1.08±0.45,继发组为2.18±1.78,甲亢组为1.16±0.75,正常对照组为6.40±5.05,组间差别有统计学意义(P≤0.01)。结论尿钾-肌酐比值是早期诊断HPP的有益指标,继而指导补钾治疗,避免治疗后出现反跳性高钾血症。Objective To observe the value of urine potassium/creatinine ratio in the early diagnosis of hypokalemic periodic paralysis （HPP）. Methods 64 cases with HPP were divided into 3 groups according to its pathogeny ： primary group, secondary group and hyperthyroidism group. 25 young healthy volunteer conducted control group. The level of blood hyperthyroidism, urine potassium and creatinine was detected, and urine potassium-creatinine ratio was compared among groups. Results The urine potassium-creatinine ratio was 1.08 ± 0.45 in the primary group,2.18± 1.78 in the secondary group, 1.16 ± 0.75 in the hyperthyroidism group, and 6.40 ± 5.05 in the control group. There was statistical difference among groups（ P = 0. 002 〈 0.01 ）. Conclusions The urine potassium-creatinine ratio has something to do with the early diagnosis of HPP. The timely supplement of potassium can provide from rebound hyperpotassemia.

关 键 词：尿钾-肌酐比值 低钾型周期性瘫痪 早期诊断 

分 类 号：R746.03[医药卫生—神经病学与精神病学]