选择性动脉插管化疗+碘油栓塞治疗30例中晚期胃癌的临床疗效对比观察  

Clinical effect of selective infusion chemotherapy and chemoembolization by artery intubation on treating advanced gastric cancer in 30 patients

作　　者：沈惠琳[1] 叶泉忠[2] 

机构地区：[1]杭州师范大学附属医院消化内科,浙江杭州310015 [2]衢州市人民医院消化内科室,浙江衢州324200

出　　处：《杭州师范学院学报（医学版）》2008年第4期238-240,共3页Journal of Hangzhou Teachers College :Medical Edition

摘　　要：目的对比研究选择性动脉插管化疗治疗中晚期胃癌的临床疗效。方法选择TNM分期属Ⅲ、Ⅳ期的中晚期胃癌患者56例分为两组,插管化疗+碘油栓塞治疗组予FAM方案选择性动脉插管化疗,常规化疗组予FAM方案常规化疗,观察两组的临床症状、转移灶的改善情况、不良反应的出现情况,并统计两组的近期缓解率及生存率。结果插管化疗+碘油栓塞治疗组的近期缓解率(CR+PR)为56.7%,高于常规化疗组的26.9%,(P<0.05),生存率无明显差异(p>0.05),不良反应的程度明显轻于对照组。结论选择性胃动脉插管化疗+碘油栓塞对于中晚期胃癌的疗效明显优于常规静脉全身化疗。Objective To evaluate the clinical effect of selective arterial infusion chemotherapy and chemoembolization on advanced gastric cancer. Methods 56 cases with advanced gastric cancer （TNM stage Ⅲ or Ⅳ） were randomly divided into two groups. 30 patients received selective arterial infusion chemotherapy and chemoembolization （Group 1） , and 26 patients received venous chemotherapy（ Group 2）. Alleviation of symptoms, metastasis, side effects and survive rate were analyzed and compared between the Group 1 and the Group 2. Results Patients in Group 1 showed higher alleviation rate （56.7% vs 26.9%, P 〈 0.05）, less side effects and similar survival ration compared with patients in the Group 2. Conclusion The effect of selective arterial infusion chemotherapy and chemoembolization is much better than that of venous chemotherapy in treatment of advanced gastric cancer.

关 键 词：胃癌 TMN分期 介入治疗 FAM方案 

分 类 号：R735.2[医药卫生—肿瘤]