PET/CT显像在宫颈癌原发灶诊断及盆腔淋巴结分期的价值  

Role of ^(18)F-FDG PET/CT in diagnosing idiopathy and detecting lymph node metastasis in pelves of cervical cancer

作　　者：卢宝彦[1] 车文颖 姚树展[1] 

机构地区：[1]山东大学附属省立医院核医学科,山东济南250021 [2]武警山东总队直属支队,山东济南250014

出　　处：《医学影像学杂志》2008年第9期1052-1054,共3页Journal of Medical Imaging

摘　　要：目的:评价18F-FDG PET/CT显像在诊断宫颈癌原发灶及盆腔淋巴结分期中的临床应用价值。方法:回顾性分析58例患者在手术前PET/CT显像结果,所有恶性肿瘤患者均经手术治疗并行盆腔淋巴结清扫,良性患者经病理及组织学证实,将PET/CT显像结果与病理结果进行对比分析。结果:58例患者中,有28例为宫颈癌,PET/CT显像真阳性24例,真阴性28例,假阴性4例,假阳性2例,与病理结果对比,PET/CT诊断宫颈癌准确率、灵敏度、特异性、阳性预测值和阴性预测值分别为87.9%、85.7%、90%、92.3%、84.3%。28例恶性肿瘤患者,手术共取出盆腔大小不同淋巴结162枚,其中转移淋巴结35枚,与病理和随访结果对比,PET/CT诊断真阳性29枚,假阳性10枚,其诊断的准确率、灵敏度、特异性、阳性预测值和阴性预测值分别为90.1%、82.9%、92.1%;74.4%、95.1%。结论:PET/CT显像对诊断宫颈癌原发灶与盆腔淋巴结转移的准确率高。Objective：To evaluate the clinical value of PET/CT in judging mediastinal lymph node metastasis in pelves of cervical cancer and determining the diagnosis of cervical cancer. Methods：A retrospective review was performed on 58 patients and all patients were evaluated with PET/CT. 28 of them were cervical cancer. All cervical cancer patients had their pelvic lymph node samples by resection. Each imaging study were evaluated and compared with histopatholegy. Results： For diagnosing the cervical cancer and detecting pelvic lymph metastasis, the rates of accuracy by PET/CT were 87.9% and 90.1% ; sensitivity was 85.7% and 82.9%. Specificity were 90% and92.1%, positive predictive value （PPV） were 92.3% and 74.4%, negative predictive value （NPV） were 84.3% and 95.1%. Conclusion： PET/CT fusion images had high accurate rate in diagnosig cervical cancer and detecting lymph node metastasis in wives of cervical cancer.

关 键 词：正电子发射断层 体层摄影术 X线计算机 宫颈癌 淋巴 转移 

分 类 号：R737.33[医药卫生—肿瘤] R814.42[医药卫生—临床医学]