早期持续肠内营养对食管癌术后患者预后的影响  

Effects of early enteral nutrition on prognosis of patients with sustained esophageal cancer

作　　者：张波[1] 张文[1] 骆学全[1] 强生庭[1] 赵志毅[1] 陈华增[1] 冼国明[1] 张峰[1] 

机构地区：[1]肇庆市第一人民医院胸心外科,广东省肇庆526021

出　　处：《中国基层医药》2008年第8期1313-1314,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨食管癌术后早期持续肠内营养支持对患者预后的影响。方法将248例食管胃底贲门癌根治手术的患者随机分为肠内营养（EN）组和肠外营养（PN）组各124例，手术后第1天开始分别给予营养支持6d，于术前1d、术后8d检测体质量、血常规、肝功能，并观察并发症的发生率。结果EN组体质量、红细胞数、血红蛋白、白蛋白等下降幅度少于PN组（P〈0．01）。EN组患者术后无吻合口瘘发生，肺部感染发生率为13．8％，胸液量平均为780ml，无切口愈合不良者；PN组患者吻合口瘘发生率3．2％，肺部感染发生率28．2％，胸液量平均为1842ml，切口愈合不良发生率7．2％。结论术后早期EN比PN对食管癌营养状况的改善更好，并发症发生率更低。Objective To investigate the effect of early enteral nutrition. Methods 248 patients with esophageal and gastric carcinoma were randomly divided into two groups, and received enteral nutrition （EN） and parenteral nutrition （PN） each continuously for 6 days after operation. The body weight, blood routine test, liver function,and postoperative day 8 were compared with those before operation. Results The body weight,red blood cell count, and the levels of hemoglobin, serum albumin and transaminase decreased less in EN group than those in PN group（ P 〈 0.01 ）. The complication rates of anastomotic fistula, pulmonary infection, and delayed incision healing and average volume of pleural effusion were 0,13.8 % , 0,780ml in EN groups, while 3.2 % , 28.2 % , 7.2 % , 1842ml in PN group. Conclusion Early postoperative enterai nutirtion after esophageal carcinoma surgery can improve nutritional status and reduce complications in comparision with parenteral nutrition.

关 键 词：食管肿瘤 外科手术 肠道营养 

分 类 号：R735[医药卫生—肿瘤]