中国成人癫痫持续状态诊治现状  

DIAGNOSIS AND THERAPY OF ADULT STATUS EPILEPTICUS IN CHINA

作　　者：陈蕾[1] 王锦华[1] 周东[1] 

机构地区：[1]四川大学华西医院神经内科,成都610041

出　　处：《现代预防医学》2008年第19期3830-3831,3834,共3页Modern Preventive Medicine

摘　　要：[目的]探讨中国成人癫痫持续状态(SE)的诊治现状。[方法]对1996年1月～2007年10月连续登记住院的16岁以上SE患者的诊治情况进行总结。[结果]共收集204例成人SE患者,诊断惊厥性癫痫持续状态(CSE)192例,非惊厥性癫痫持续状态(NCSE)12例。76.47%的患者SE发作超过1h后才开始治疗,其中32例患者在发作20h后才开始治疗。抗惊厥药物治疗包括:地西泮静脉治疗,苯巴比妥肌肉注射,丙戊酸钠静脉治疗,麻醉治疗。最后死亡29例。[结论]该院诊断的NCSE比例远低于欧美国家。治疗前SE持续长于欧美国家。该院抗惊厥治疗方案与欧洲指南差距大,患者死亡率高。因此,需要提高对SE的认识,借鉴他国诊疗指南,提高中国诊治水平。[Objective] To explore the diagnosis and therapy of adult status epilepticus （SE） in China. [Methods] Continuously registered the clinical materials of SE patients in a hospital during January 1996 to July 2007. [ Results] Of all the 204 registered patients, 192 patients were diagnosed as convulsive status epileptieus （CSE）, only 12 eases were non- convulsive status epileptieus （NCSE） . 76.47% of them were not treated within 1 hour, with 32 patients were treated after 20 hour post-SE. [Conclusion] The incidence or the diagnosed NCSE is lower than United States and Europe. The duration before anticonvulsant therapy is longer and the mortality is higher than these countries. The treatment gap is far from Europe treatment guideline for SE, so we need to study some good guidelines in other countries to improve our level of diagnosis and therapy for SE.

关 键 词：中国 成人 癫痫持续状态 诊断 治疗 

分 类 号：R742.1[医药卫生—神经病学与精神病学]