牙龈上皮细胞的抗菌防御作用  

Antimicrobial defense effects of gingival epithelial cells

作　　者：章立群[1] 李德懿[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院口腔医学研究所,上海200011

出　　处：《国际口腔医学杂志》2008年第5期519-522,共4页International Journal of Stomatology

基　　金：国家自然科学基金资助项目(30672314)

摘　　要：牙龈上皮细胞不仅具有屏障作用,还具有先天免疫抗菌功能,如牙龈上皮细胞表面受体的信号传递、分泌抗菌多肽、蛋白酶和细胞因子等。下面就Toll样受体、抗菌多肽或蛋白、细胞因子或趋化因子、蛋白酶等与牙龈上皮细胞关系的研究进展作一综述,旨在加强对牙龈上皮细胞防御机制的认识。Gingival epithelial cells dose not provide a physical barrier to infection, it also has an active role in innate host defense. For example epithelial cell can transfer signals through ceil surface receptor, produce and release antimcrobial peptides, proteinase, cytokines and etc. In order to strengthen the understanding of the defense mechanism of gingival epithelium, this article makes a summary on the relationship of gingival epithelial cells with the Toll-like receptor, antimcrobial peptides, cytokines and proteinase .

关 键 词：牙龈上皮细胞 先天防御 TOLL样受体 抗菌多肽 细胞因子 

分 类 号：R780.2[医药卫生—口腔医学]