肺癌骨转移临床病理特性的探讨  

Study on the Clinical Pathologic Character of the Lung Cancer Patients with Osseous Metastases

作　　者：赵锡江[1] 王凤明[1] 姜宏景 张熙曾[1] 

机构地区：[1]天津市肿瘤医院

出　　处：《齐鲁肿瘤杂志》1997年第4期266-268,共3页

摘　　要：１９８５年１月～１９９３年１月收治资料完整的肺癌骨转移病人８５例，其中腺癌３４例，小细胞未分化癌２６例，鳞癌２０例，其它癌５例。骨痛是肺癌骨转移的最主要的表现形式（８１．２％），次之为神经系统症状和病理性骨折。肺癌骨转移与病理类型有关：腺癌最常见（４０．０％），小细胞未分化癌（３０．５％），鳞癌（２３．５％）。骨转移的常见的好发部位依次为肋骨（４８．２％）、胸椎（３９．９％）、腰椎（３５．３％）和骨盆（３１．６％）。病灶以多发转移为主（７８．９％）。放射性核素骨显影对肺癌骨转移的诊断价值优于Ｘ线。肺癌骨转移的治疗以对症治疗和局部治疗为主，对一般情况较好者，可补加特异性治疗．所有病人的平均生存时间为２．７个月。单一与多发二者的生存期分别为３．３个月和２．１个月；局部治疗对生存期也无明显的影响。自确诊后的１年生存率为５．３％，２年生存率为２．１％，３年生存率为０。Eighty-five lung cancer patients with osseous metastases(34 adenocarcinomas,26 SCLC,20 squamous cell carcinomas and 5 others)have been treated in Chest Department of Tianjin Cancer Hospital from Jan.1985 to Jan.1993.The major symptoms of osseous metastases were pain,nervous system signs and pathologic bone fractures.The osseous metastases is concerned with the pathological type of lung cancer.The common sites of metastases were respectively ribs (48.2%),thoracic vertebrae(39.9%),lumbar vertebrae(35.3%)and pelvis (31.6%).The lesions were multiple in the most cases(78.9%).Radionuclide bone imaging was supperior to X-ray in detecting osseous metastases of lung cancer.The treatments were mainly for symptoms and for local lesions.For the patients who had a good general conditions,we could give specific theray.The average survival for all patients was 2.7months for patients with multiple lesions.The local treatment hadn't significant influence for survival.The 1-,2-and 3-year survival rates from time of diagmosis were respectively 5.3%,2.1%and 0%.

关 键 词：肺肿瘤 肿瘤转移 病理 骨转移 

分 类 号：R734.2[医药卫生—肿瘤] R738.1[医药卫生—临床医学]