鼻咽癌腔内微波加热的实验研究  

AN EXPERIMENTAL STUDY OF TREATING NASOPHARYNGEAL CARCINOMA WITH INTRACAVITARY MICROWAVE HYPERTHERMIA

作　　者：吴敬波[1] 陈成钦[2] 钟强荣[2] 

机构地区：[1]泸州医学院附属医院肿瘤科,646000 [2]中山医科大学肿瘤医院放疗科

出　　处：《泸州医学院学报》1997年第1期30-33,共4页Journal of Luzhou Medical College

摘　　要：在肌肉体模上测定GXH-Ⅰ型2450MHz微波热疗机鼻咽腔条形辐射器的热分布，发现辐射器明显升温的范围在其顶端与顶端后2cm之内.最大升温点在顶端及其附近.在肌肉体模制作的鼻咽腔上测得该辐射器可使鼻咽侧壁与顶后壁0.5cm深度处分别升温9.6℃、5.6℃.鼻咽腔肌肉模与兔大腿肌肉上模拟的人鼻咽腔上测得该辐射器的有效活热深度为0.5～1cm。在患者鼻咽原发肿瘤内连续测温中发现.肿瘤内选择性升温时间在治疗30分钟后出现，肿瘤表面温度46℃左右，肿瘤内0.3cm深度处温度达50℃左右，选择性升温效果明显.Heating pattern of the nasopharyngeal applicator for microwave hyperthermia (f=2450MHz) was evaluated on a muscle phanton. Maximum ascenting points of temperature were near the tip of applicator and the effective heating range of 2cm was abserved. In a muscle phanton of nasopharynx, the temperature ascented by 7. 3℃ and 4. 8℃ at 0. 5cm depth under the suurface of lateral wall and post-vertical wall respectively. The effective therapeutic heating depth of nasopharyngeal applicator ranged from 0. 5 to 1. 0cm in the muscle phanton of nasopharynx and in a rabbit's muscle cavity imitating human nasopharynx. The selective temperature ascent was observed after heating for 30 minutes in the primary lesion of a patient with nasopharyngeal carcinoma. At the time, the temperature near the surface of primary tumor was about 46℃, but the temperature increased to about 50℃ in 0. 3cm depth under the surface of the primary tumor. The selective temperature asent in the Primary tumor was obvious.

关 键 词：鼻咽肿瘤 腔内热疗 微波加热 实验研究 

分 类 号：R739.630.5[医药卫生—肿瘤]