恶性肿瘤相关凝血功能紊乱与抗凝治疗  

Malignant tumor-related coagulation disorder and anticoagulation therapy

作　　者：常春霞(综述)[1] 陈洪(审校)[1] 

机构地区：[1]东南大学临床医学院附属中大医院消化科,南京210009

出　　处：《国际肿瘤学杂志》2008年第9期677-680,共4页Journal of International Oncology

基　　金：基金项目：江苏省中医药局科技基金资助项目（HL07067）;东南大学科技基金资助项目（KJ0790295）

摘　　要：凝血功能紊乱与恶性肿瘤之间相互影响、相互促进，最终形成一个严重影响肿瘤患者预后的恶性循环。凝血功能紊乱与恶性肿瘤相互作用关系的日趋明朗使抗凝成为肿瘤治疗的一个新的突破口。大量实验室及临床研究显示，抗凝治疗能抑制肿瘤发生、发展，改善肿瘤患者的预后。但针对不同患者、不同种类的抗凝剂，抗凝治疗的有效性及安全性尚有待进一步深入的研究。Coagulation disorder plays an important role in the development of maliguant tumors, and vice versa. This induces an vicious circle which affects the prognosis of the patients seriously. Anticoagulation becomes a new way for malignant tumor therapy as the relationship between coagulation disorder and malignant tmnor becomes more and more clear. Lots of laboratory and clinical studies indicate that anticoagulation therapy could suppress the genesis and development of malignant tumors and thus improve the patients＇outcome. But for different patients and different anticoagulants, deeper study is needed considering the effect and safety of this therapy.

关 键 词：肿瘤 药物疗法 血栓形成 

分 类 号：R730.22[医药卫生—肿瘤] R730.53[医药卫生—临床医学]