婴儿促纤维增生型星形细胞瘤1例并文献回顾  

Desmoplastic infantile astrocytoma:1 case report and review of literature

作　　者：姚丽[1] 巩丽[1] 张伟[1] 尚凤霞[1] 朱少君[1] 

机构地区：[1]第四军医大学唐都医院病理科,陕西西安710038

出　　处：《现代肿瘤医学》2008年第10期1673-1674,共2页Journal of Modern Oncology

摘　　要：目的:探讨婴儿促纤维增生型星形细胞瘤病理形态特征及鉴别要点。方法:报道1例婴儿促纤维增生型星形细胞瘤并结合文献对其组织学和免疫组织化学特点进行研究。结果:本例婴儿促纤维增生型星形细胞瘤头颅CT表现为右侧额骨及顶骨局部骨质缺损,右侧大脑半球多囊性占位性病变。组织学表现为梭形肿瘤细胞,形似纤维细胞或纤维母细胞,排列呈束,编织样。免疫组织化学显示:瘤细胞呈胶质酸性蛋白(GFAP)阳性,波形蛋白(Vimentin)阳性,S-100蛋白阳性。结论:婴儿促纤维增生型星形细胞瘤是一种比较罕见的发生于婴幼儿的脑部肿瘤,根据其临床特点及组织学和免疫组织化学特征可以进行明确诊断。Objective：To study the pathological characteristics of desmoplastic infantile astrocytoma. Methods： One case of desmoplastic infantile astrocytoma was reported and the pathological features were studied by microscopy and immunohistochemistry. Results ： In this case, CT scan showed local loss of fight frontal bone and os parietale, cystic mass in the fight cerebral hemisphere. Histologically, the tumor cells looked like fibrocytes or fibroblasts grew in bundles and nests. Immunohistochemistry showed that the tumor cells were positive for GFAP, Vimentin and S - 100. Conclusion： Desmoplastie infantile astrocytoma is a rare infantile brain tumor and can be diagnosed by its characteristics of histology and immunohistochemistry.

关 键 词：婴儿促纤维增生型星形细胞瘤 免疫组织化学 

分 类 号：R730.264[医药卫生—肿瘤]