胆道支架置入联合内外放疗治疗恶性阻塞性黄疸的临床观察  

Biliary stent implantation plus internal or external radiotherapy in malignant obstructive jaundice

作　　者：吴海江[1] 管峦[1] 崔宁[1] 曹驰[1] 刘凌[1] 董超[1] 骆勇[1] 

机构地区：[1]东南大学医学院附属徐州医院江苏省徐州市中心医院介入科,221009

出　　处：《中华全科医师杂志》2008年第10期707-708,共2页Chinese Journal of General Practitioners

摘　　要：对30例恶性阻塞性黄疸病例分别行胆道支架置人＋后装腔内放疗＋适形放疗（综合组，15例）和单纯胆道支架置入治疗（对照组，15例）。两组患者血总胆红素在胆道支架置入后1个月内明显下降，对照组6个月后开始升高，而综合组6个月后继续降低；肿瘤最大径对照组增大，综合组缩小。对照组无完全与部分缓解，综合组肿瘤缓解比例为13／15；综合组0．5年、1年和2年生存比例分别为15／15，14／15，和10／15，高于对照组的15／15，5／15和1／15。Thirty patients with malignant obstructive jaundice were treated with biliary stent implantation ＋ brachytherapy ＋ conformal radiotherapy （study group; n = 15 ） or biliary stent implantation alone （control group; n = 15）. Total bilirubin （TBIL） levels significantly declined within 1 month in both groups. However, at 6 months, TBIL values began to increase in the control group and continuously declined in the study group. Maximum tumor diameter increased in the control group, while decreased in the study group （remission rate, 13/15）. As for the study group, the survival rate at O. 5, 1, and 2 years was 15/15, 14/15, and 10/15, respectively, higher than the control group （ 15/15,5/15,and 1/15） . Combining biliary stent implantation with braehytherapy and conformal radiotherapy might be a safe and effective treatment of choice for patients with malignant obstructive jaundice.

关 键 词：黄疸 阻塞性 支架 临床分析 

分 类 号：R730[医药卫生—肿瘤]