高IgE综合征并发深部真菌病  

Hyperimmunoglobulinemia E syndrome with subcutaneous chronic mycosis

作　　者：张凡[1] 武玲慎[1] 万哲[1] 徐辉[1] 杨勇[1] 李若瑜[1] 涂平[1] 

机构地区：[1]北京大学第一医院皮肤性病科,北京100034

出　　处：《临床皮肤科杂志》2008年第10期672-674,共3页Journal of Clinical Dermatology

摘　　要：报告1例高IgE综合征并发深部真菌病。患者男,24岁。躯干和四肢出现大量红斑、丘疹和斑块23年,皮下及淋巴结肿物4年。实验室检查:血IgE>5000kU/L。皮损组织病理检查示慢性皮炎改变,真皮内有较多嗜酸性粒细胞浸润。腹股沟淋巴结肿物银染检查镜下可见许多菌丝、假菌丝、孢子。A case of hyperimmunoglobulinemia E syndrome with subcutaneous chronic mycosis is reported. A 24-year-old male patient presented with erythema, paplues and patches on his extremities and trunk for 23 years, subcutaneous nodule and inguinal swollen lymph nodes for 4 years. His peripheral blood eosinophils and serum IgE levels were high. Skin biopsy revealed that chronic dermatitis changes and eosinophils could be seen in the dermis. Silver staining of inguinal swollen lymph node in the revealed hyphae, pseudohyphae and spores.

关 键 词：高IGE综合征 真菌病 淋巴结 

分 类 号：R593.3[医药卫生—内科学] R756.6[医药卫生—临床医学]