成年近视眼人群角膜Q值的观察分析  

The Q value of cornea in adults with myopia ZHAO

作　　者：赵菁芳[1] 王泽欧 

机构地区：[1]辽宁医学院附属第一医院眼科,锦州121001 [2]解放军第205医院眼科

出　　处：《眼科》2008年第5期308-310,共3页Ophthalmology in China

摘　　要：目的分析成年近视眼人群角膜Q值的分布情况及其与年龄、性别、眼别、屈光度的关系。设计前瞻性病例系列。研究对象连续的成年人近视眼510例(1020眼)。方法应用OrbscanⅡz跟前节分析系统检测近视眼病例的角膜Q值。对Q值行正态分布检验,并做眼别间、性别间比较,对球镜屈光度、柱镜屈光度、年龄与Q值之间进行相关分析。主要指标角膜Q值,相关系数。结果成年近视眼1020眼角膜Q值平均-0.270±.16(范围-0.86～0.25),近似正态分布。右眼与左眼间比较差异无统计学意义(P=0.675)。角膜Q值男性(-0.26±0.15)与女性(-0.27±0.17)间比较差异无统计学意义(P=0.697)。角膜Q值与球镜屈光度、柱镜屈光度无相关性(r=0.057,0.044;P=0.068,0.156)。20岁以下组角膜Q值平均为-0.24,负值较小;40岁以上组为-0.36,负值较大,与其他组比较差异有统计学意义(P均=0.000)。结论成年近视眼人群的角膜Q值随年龄增长有逐渐向负值飘移的倾向,尤其40岁以后更明显。角膜Q值与眼别、性别、屈光度无关,但高度个性化。Objective To observe the distribution of cornea Q value in adult myopia, and its relationship with age, sex, eye and refraction. Design Prospective case series. Participants Consecutive 510 patients （1020 eyes） of myopia of adults. Methods Cornea Q values were obtained with Orbscan II z Anterior Segment Analysis System in all subjects of adult myopia. Normal distribution test of Q value and correlation analysis with sphere, cylinder, sex, and age were performed. Main Outcome Measures Q value of cornea, correlation coefficient. Results In 1020 eyes of adult myopia, the mean Q value was -0.27±0.16 （ range from -0.86 to 0.25 ） with near norreal distribution. The difference of Q value between right eyes and left eye was not statistically significant （P=-0.675）. The Q value between male （-0.26±0.15） and female（-0.27±0.17） was not statistically difference（P=0.697 ）. No significant relation was found Q value with either sphere （r=0.057, P=0.068） or cylinder （r=0.044, P=0.156）. Mean Q value of below 20 years old was maximal, - 0.24, while over 40 years old was minimal, -0.36, and the difference were statistically significant （P=0.000）. Conclusions Q value of cornea has negative shift with the increase of age, especially in over 40 years old. Q value of cornea has no relationship with left or right eyes, sex and refraction, but it is highly customized.

关 键 词：近视眼 角膜Q值 临床分析 治疗方法 

分 类 号：R778.11[医药卫生—眼科]