经皮肝穿刺胆道内支架置入术结合动脉化疗栓塞术治疗恶性胆道梗阻  

Percutaneous transhepatic in insertion of metalic stent and arterial chemoemblization for malignent biliary obstruction

作　　者：欧盛秋[1] 马亦龙[1] 康平[1] 李志坤[1] 蒙志斌[1] 欧阳欣[1] 

机构地区：[1]广西医科大学附属肿瘤医院介入治疗科,南宁530021

出　　处：《重庆医学》2008年第19期2215-2216,共2页Chongqing medicine

摘　　要：目的观察经皮肝穿刺胆道内支架置入术结合动脉化疗栓塞术的双途径介入治疗恶性胆道梗阻的临床疗效。方法对24例恶性胆道梗阻的患者在经皮肝穿刺胆道内支架置入术的基础上，结合动脉化疗栓塞术的双途径介入治疗，随访并观察近中期疗效和生存期。结果24例患者共置入网状支架35枚；置入术后血清总胆红素水平较置入术前明显下降（P〈0．01）；内支架置入术后进行动脉化疗栓塞术1～4次（平均2．2次）；随访2～30个月，死亡16例，平均生存期为12．9个月，8例仍存活；开通时间平均为249d，半年开通率为75％。结论经皮肝胆道内支架置入术结合动脉化疗栓塞术的双途径介入可有效地治疗恶性胆道梗阻，明显缓解黄疸，延长支架开通时间及患者生命。Objective To valuate the therapeutic effect of percutaneous transhepatic insertion of biliary setents and arterial chemoembolization for treatment of malignant biliary obstruction. Methods Percutaneous transhepatic insertion of biliary stents and arterial chemoembolization were performed in 24 patients with malignant biliary obstruction. The early and late therputic effects were observed in 2-30 months follow up periods（P〈0.01）. Results Twenty-four stent were placed in 24 patients. Serum total hilirubin decreased significantly treated by percutaneous transhepatic stent implantation in the first two week. Transarterial chemoemholization were done one to four times with average of 2.2 times after stent implantation. All patients were followed up with an average of 12.9 months,including 8 patients alive. The mean patency time was 249 days, the ratio of half-year patency was 75 %. Conclusion Percutaneous transhepatic insertion of hiliary setents eomhined arterial ehemoembolization was is safe and effective palliative therapy in patients with malignant biltary obstruction. It can make patients have longer stent patency time and live time.

关 键 词：介入性 胆道内支架 化疗栓塞 恶性胆道梗阻 

分 类 号：R735[医药卫生—肿瘤]