色素内镜对早期胃癌及癌前病变的诊断价值  

Value of pigmental endoscopy in early stage gastric cancer and precancerous lesions

作　　者：张欣[1] 王国祥[1] 王建文[1] 王宏刚[1] 

机构地区：[1]浙江省台州市立医院消化内科,浙江台州318000

出　　处：《胃肠病学和肝病学杂志》2008年第10期820-820,823,共2页Chinese Journal of Gastroenterology and Hepatology

摘　　要：研究内镜下美蓝染色对早期胃癌及癌前病变的诊断价值。内镜下有黏膜异常表现的120例患者,54例予以美蓝染色后活检,66例单纯活检。美蓝染色组病检证实有肠化萎缩者占23例,不典型增生15例,早期胃癌4例(均经手术病理证实);单纯活检组(对照组)病理证实有肠化萎缩者占18例,不典型增生10例,未检出早期胃癌。染色组早期胃癌及癌前病变检出率为77.78%,对照组为40.90%,两组差别有显著性差异(P<0.05)。结果表明,应用色素内镜指导黏膜活检,可显著提高早期胃癌和癌前病变的检出率。To evaluate the value of methylene blue staining in early gastric cancer and precancerous lesions. Gastric mucosa biopsy were performed by endoscopy in 120 patinets with abnormal gastric mucosa. In 54 of these 120 patients, the biopsy was done according to the result of 0.5% methylene blue staining. Among the 54 patients, 23 cases were intestinal metaplasia, 15 dysplasia, 4 early gastric cancer （ comfirmed surgically）. Among the 66 patients （ the control group） , 18 cases were intestinal metaplasia, 10 dysplasia but no gastric cancer. The diagnostic rates of gastric cancer and precancerous lesions were significantly different which were 77.78% in methylene blue staining group and 40.90% in control group. The results was different significantly （P 〈 0.05 ）. Pigmental endoscopy could be useful in the diagnosis of early gastric cancer and precancerous lesions.

关 键 词：色素内镜 早期胃癌 肠上皮化生 不典型增生 黏膜活检 

分 类 号：R730.4[医药卫生—肿瘤] R735.2[医药卫生—临床医学]