止血明胶对高频电切治疗宫颈上皮内瘤样变术后创面恢复的价值  

Clinical observation of cut healing with gelatin paste after cervical intraepithelial neoplasia surgery by LEEP

作　　者：陈瑶[1] 卓静[1] 李淳[3] 黄明通[2] 黄慧君[4] 

机构地区：[1]汕头大学医学院第二附属医院妇产科,广东省汕头515041 [2]汕头大学医学院第二附属医院心血管内科,广东省汕头515041 [3]汕头大学医学院病理科 [4]汕头大学医学院第一附属医院

出　　处：《中国基层医药》2008年第9期1409-1410,共2页Chinese Journal of Primary Medicine and Pharmacy

基　　金：广东省医学科研课题（A2005451）

摘　　要：目的观察止血明胶对高频电切（LEEP刀）治疗宫颈上皮内瘤样变（CIN）创面愈合、预防术后出血的临床效果，寻找预防LEEP刀治疗CIN后创面并发症的有效方法。方法100例宫颈上皮内瘤样变病例，应用LEEP刀手术后，随机分成治疗组60例，对照组40例，治疗组的创面采用止血明胶粘贴，对照组的创面采用纱布填塞，观察术后两组短期阴道出血、感染及宫颈修复情况。结果治疗组60例，阴道出血0例，感染0例，宫颈修复不良0例；对照组40例，短期阴道出血3例，感染2例，宫颈修复不良3例；两组术后阴道出血、感染及宫颈修复不良发生率比较差异有统计学意义（P〈0．05）。结论LEEP刀治疗CIN后，采用止血明胶粘贴处理创面可减少阴道出血、感染及宫颈修复不良并发症的发生。Objective To observe the post-operative clinical inpact on cervical intraepithelial neoplasia surgery by Loop electrosurgical excision procedure（LEEP） ,gelatin paste to improve the healing of the cut, prevent the post-operative bleeding, and find out effective methods of preventing LEEP complications. Methods 100 patients with cervical intraepithelial neoplasia underwent LEEP in clinic. Divide them into two groups randomly, 60 patients were adopted gelatin paste post-LEEP as the cure group, while 40 patients were adopted as control group. Observation Vaginal bleeding, infection and cervical repair in short-term. Results In 60 patients of cure group, never patients with vaginal bleeding, infection and the cut healing in the short time. In 40 patients of control group, three patients with vaginal bleeding, two patients with infection, and three patients with bad healing. The different between two group with vaginal bleeding, infection and the cut healing time was significant （ P 〈 0.05 ）. Conclusion gelatin paste can reduce bleeding, infection and cervical repair bad complications after cervical intraepithelial neoplasia surgery by LEEP.

关 键 词：宫颈上皮内瘤样病变 明胶 电凝术 伤口愈合 

分 类 号：R737[医药卫生—肿瘤]