赣榆县胃癌影响因素1:1配对病例对照研究  

A 1:1 Matched Case-control Study on Risk Factors for Stomach Cancer in Ganyu County

作　　者：王旭善[1] 吴德林[1] 张晓峰[1] 顾绍升[1] 金凤[1] 潘振庆[1] 武鸣[2] 覃玉[2] 

机构地区：[1]赣榆县疾病预防控制中心,江苏赣榆222100 [2]江苏省疾病预防控制中心慢病科,江苏南京210009

出　　处：《中国慢性病预防与控制》2008年第5期477-478,共2页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：江苏省医学135工程重点人才研究基金资助项目(RC 2003090)

摘　　要：目的探讨赣榆县胃癌危险因素及保护因素,为该地区胃癌防治工作提供依据。方法对319例新发胃癌病例及其1:1配对的健康对照者进行相关因素调查,应用条件Logistic回归对相关因素进行分析。结果胃癌的主要危险因素为进食热烫食物(OR=2.21,95%CI:1.57～3.12)、上消化道炎症患病史(OR=4.26,95%CI:2.59～7.03)、癌症家族史(OR=2.29,95%CI:1.37～3.82);主要保护因素为经常生吃大蒜(OR=0.64,95%CI:0.42～0.96)、经常饮茶(OR=0.37,95%CI:0.25～0.54)。结论胃癌的发病与不良的膳食习惯、上消化道炎症及癌症家族史有关,生吃大蒜和饮茶能有效预防胃癌的发生。Objective To explore the risk factors and protective factors for stomach cancer in Ganyu county. Methods Data of 319 pairs of new stomach cancer cases and health controls （1：1 matched） were studied by conditional Logistic regression method on the influential factors. Results The main risk factors for stomach cancer were the habits of eating hot foods （OR = 2.21, 95%CI： 1.57N3.12）, the history of upper gastrointestinal inflammation （4.26, 2.59N7.03）, family history of cancer （2.29, 1.37-3.82）; The main protective factors were often eating raw garlic （0R=0.64, 95%CI： 0.42-0.96）, regular drinking tea（0.37, 0.25-0.54）. Conclusion Unhealthy dietary habits, the history of upper gastrointestinal inflammation and family history of cancer are related to stomach cancer, while eating raw garlic and regular drinking tea may be effective in preventing the occurrence of stomach cancer. The results could be applied in stomach cancer prevention activities in Ganyu county.

关 键 词：胃癌 危险因素 病因学 病例对照研究 

分 类 号：R735.2[医药卫生—肿瘤]