激光辐照下皮肤组织光热响应有限元分析  

Research on Opto-Thermal Response of Human Skin Irradiating by CW and Plused Laser Based on FEM Simulation

作　　者：丁海峰[1] 黄梅珍[1] 童雅星[1] 李振庆[1] 谢树森[2] 龚玮[2] 

机构地区：[1]上海交通大学物理系光学工程研究所,上海200240 [2]福建师范大学医学光电科学与技术教育部重点实验室,福建福州350007

出　　处：《光学学报》2008年第10期1983-1988,共6页Acta Optica Sinica

基　　金：国家自然科学基金(60678054);医学光电科学与技术教育部重点实验室开放基金(JYG0815)资助课题

摘　　要：为了更好地选择临床激光医疗曝光参量,采用有限元数值计算方法,模拟了脉冲激光与连续激光对人皮肤组织的光热作用及导致的温度变化效应,比较了两者的不同,得到了热响应时间及热弛豫时间与组织深度的关系,即组织越深(0～60μm),其热响应时间(0～4 ms)与热弛豫时间(0.4～12.1 ms)越长;分析了激光脉宽长短对组织升温的影响;建立了评价脉冲间热损失的评价函数δ,并以此对脉冲间隔的选取作了探讨。To obtain better laser exposal parameters in the laser medicine clinic, a finite-element method was adopted to simulate the human skin＇s opto-thermal response when irradiated by pulsed laser and continuons-wave （CW） laser. The differences of tissue temperature caused by pulsed laser and CW laser were compared. The relationships between thermal response time, thermal relaxation time and depth of skin were achieved. With increasing the skin＇s depth （0～60 μm）, the thermal response time （0～4 ms） and relaxation time （0.4～12.1 ms） became longer. The temperature rise of tissue induced by different pulse width was studied. An evaluation function δ was established to evaluate the loss of heat. Based on δ, the selection of pulse interval was analyzed.

关 键 词：生物光学 辐射曝光剂量 有限元方法 热弛豫时间 评价函数 

分 类 号：R318.51[医药卫生—生物医学工程]