肾上皮样血管平滑肌脂肪瘤3例临床病理观察  

Renal epithelioid angiomyolipoma:a clinicopathological analysis of 3 cases

作　　者：杨秀萍[1] 潘华雄[1] 郭涛[1] 贺骏[1] 翁密霞[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院病理科,武汉430022

出　　处：《临床泌尿外科杂志》2008年第9期687-689,共3页Journal of Clinical Urology

摘　　要：目的:探讨肾上皮样血管平滑肌脂肪瘤(Angiomyolipoma,AML)的临床病理特征及鉴别诊断依据。方法:回顾性分析3例肾上皮样AML的临床和病理改变状况,以及组织形态及免疫标记物的表达特点。结果:3例术前影像学检查均考虑为肾癌,镜下肿瘤内均缺乏脂肪组织,可见特征性的血管结构以及上皮样肿瘤细胞围绕血管呈袖套样排列,免疫组织化学染色示肿瘤细胞HMB45或Melan-A弥漫阳性,SMA阳性表达不定。结论:肾上皮样AML是一种少见的具有恶性潜能的肿瘤,诊断中需要注意与肾细胞癌相鉴别。免疫组织化学染色是诊断肾上皮样AML的一项必不可少的技术手段。Objective：To investigate the clinicopathologic features and differential diagnosis of the renal epithelioid angiomyolipoma. Methods： The clinicopathologic features, morphology, immunohistochemistry were studied. Results： Preoperative imaging examination ,three cases were given to renal cell carcinoma. There is a proliferation of epithelioid cells arranged in sheets, often with perivascular cuffing of epithelioid cells. The blood vessels are thick walled and lack the normal elastic content of arteries. All cases lack the lipomatous component, All tumors were immunoposltive for HMB45 and Melan A, but SMA expression uncertain. Conclusions： Epithelioid angiomyolipoma is a rarely potentially malignant mesenchymal neoplasm. It needs to differential diagnosis with renal cell carcinoma. Immunohistochemical staining is an essential technology in the diagnosis of the renal epithelioid angiomyolipoma.

关 键 词：肾上皮样血管平滑肌脂肪瘤 组织学 免疫组织化学 

分 类 号：R737.11[医药卫生—肿瘤]