原发性闭角型青光眼胰岛功能的研究  

Pancreatic Islet Function in Primary Angleclosure Glaucoma

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作  者:乔智[1,2] 朱世明[1,2] 王红梅[1,2] 

机构地区:[1]山东医科大学附属医院眼科 [2]济南市中心医院

出  处:《眼科研究》1997年第4期262-263,共2页Chinese Ophthalmic Research

摘  要:目的探讨原发性闭角型青光眼与糖代谢之间的关系。方法检测36例原发性闭角型青光眼患者和40例正常人的口服葡萄糖耐量试验(葡萄糖75g)及血清胰高血糖素、C—肽和皮质醇水平。结果病人组糖耐量异常率及空腹血糖和血清皮质醇水平比正常对照组明显增高(P<0.05~P<0.01),而血清胰高血糖素及C—肽水平却未相应增高。结论原发性闭角型青光眼患者的胰岛功能减退,应注意改善该病患者的胰岛功能和纠正糖耐量异常。ObjectiveTo investigate the relation between primary angleclosure glaucoma and glucose metabolism.MethodsThe oral glucose tolerance test(OGTT,glucose 75 g)and the serum levels of glucagon,Cpeptide and cortisol were measured in 36 patients with primary angleclosure glaucoma and 40 agematched normal controls.ResultsThe percentage of impaired glucose tolerance and the serum level of cortisol were significantly higher in glaucoma than in the normal controls(P<0.05~P<0.01).The serum levels of glucagon and Cpeptide were not significantly different between the two groups.ConclusionIt is indicated that the pancreatic islet function is insufficient in glaucoma.It could be important for the patients with primary angleclosure glaucoma to improve the pancreatic islet function and glucose tolerance.

关 键 词:闭角型青光眼 胰岛功能 葡萄糖耐量 青光眼 

分 类 号:R775.2[医药卫生—眼科] R446.19[医药卫生—临床医学]

 

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