儿童非霍奇金淋巴瘤64例临床分析  

Analysis of the 64 Patients with Non-Hodgkin's Lymphoma in Children

作　　者：赵银霞[1] 郑漪[1] 余佳宁[1] 

机构地区：[1]宁夏医学院附属医院儿科,银川750004

出　　处：《宁夏医学院学报》2008年第5期591-592,共2页Journal of Ningxia Medical College

摘　　要：目的探讨儿童非霍奇金淋巴瘤(NHL)的临床特点。方法回顾性分析64例小儿NHL临床表现、发病特点和病理分型及其治疗、预后。结果本组临床Ⅰ、Ⅱ期12例,Ⅲ、Ⅳ期52例,以浅表淋巴结肿大为首发症状38例,病理类型中以淋巴母细胞型最多见(29.69%),易发生骨髓浸润和中枢神经系统侵犯。64例NHL共放弃46例,占71.9%。NHL确诊后放弃治疗15例,死亡10例,失访5例。参加治疗49例中中途放弃治疗31例,随访23例,22例死亡,仅1例存活,其它8例失访。坚持治疗18例,在治疗中死亡5例,存活13例。结论儿童NHL恶性度高,早期易误诊,预后与疾病分期、病理及治疗相关。Objective To sum up Non-Hodgkin Lymphoma clinical characteristics in children. Methods Make a retrospective analysis of the clinical manifestation, features, pathology types, and therapy, prognosis of 64cases of Non-Hodgkin Lymphoma in Children. Results Among 64cases, 12 eases were in stage Ⅰ , Ⅱ and 52 cases were in stage Ⅲ, Ⅳ. The first attack symptom is swelling of surface lymph nodes in 38 cases. Mainly pathologic type was lymphoblastic lymphoma, NHL was easy to invade marrow and central nervous system. Conelusions It is easy to make early clinical misdiagnosis, prognosis of NHL relate closely with it clinical stage and the treatment measure.

关 键 词：非霍奇金淋巴瘤 儿童 治疗 

分 类 号：R733.1[医药卫生—肿瘤]