冷冻自体病变骨再植在颅面骨肿瘤治疗中的应用：附4例报道  

Application of autologous bone fresh-frozen and re-implantation in treatment of cranio-maxillofacial bone tumors:report of 4 cases

作　　者：陈舜岳[1] 刘治慧[1] 卢宇[1] 胡永杰[2] 

机构地区：[1]浙江省台州市立医院口腔科,浙江台州318000 [2]上海交通大学医学院附属第九人民医院·口腔医学院口腔颌面外科,上海200011

出　　处：《上海口腔医学》2008年第5期545-547,共3页Shanghai Journal of Stomatology

摘　　要：目的:探讨冷冻自体骨再植在颅面骨肿瘤治疗中的应用价值。方法:4例颅面骨肿瘤患者,其中1例为额骨肿瘤,3例为下颌骨肿瘤。采用截骨术+冷冻病变骨再植+钛板内固定方法,切除骨肿瘤后重建骨缺损。结果:4例患者术后10～14d时,创口均一期愈合,除1例于术后2个月发生病理性骨折外,其余3例经6个月～3a随访,骨块愈合良好,无肿瘤复发,颅颌面外形满意。X线片示死骨被吸收,代之以新骨形成。结论:冷冻自体骨再植是治疗颅面骨肿瘤的一种可行方法,尤其适合年轻患者。在根治肿瘤的同时可一期重建骨缺损,有较好的临床应用价值。PURPOSE： To evaluate the application of autologous bone fresh-frozen and re-implantation in treatment of cranio-maxillofacial bone tumors. METHODS： Four cases with cranio-maxillofacial bone tumors, including one in the frontal bone and three in the mandible, underwent osteoectomy, autologous diseased bone fresh-frozen by nitrogen, reimplantation of the bone and internal fixation by titanium plate to treat the bone tumor and reconstruct the bone defect. RESULTS： All four cases had one-stage healing 10-14 days after operation. One patient had pathological bone fracture 2 months postoperatively, the other three patients were well-cured without tumor recurrence and gained satisfied cosmetic appearance during 6 months to 3 years of follow-up. The X-ray films showed that the frozen bone was substituted by new bone formation. CONCLUSIONS： Autologous bone fresh-frozen and re-implantation is a feasible method in cranio- maxillofacial bone tumor treatment, especially for young patients. It make possible to do radical surgery and reconstruct the bone defect simultaneously, and is thus worthy of clinical application.

关 键 词：颅面骨肿瘤 冷冻外科:骨再植 

分 类 号：R739.8[医药卫生—肿瘤]