无梗五加果化学成分的研究(英文)  

Studies on the Chemical Constituents of the Fruit of Acanthopanax sessiliflorus(Rupr.et Maxim.) Seem.

作　　者：安琪[1] 杨春娟[1] 宋洋[1] 于凯[1] 熊志立[1] 李发美[1] 

机构地区：[1]沈阳药科大学药学院,沈阳110016

出　　处：《天然产物研究与开发》2008年第5期765-769,共5页Natural Product Research and Development

摘　　要：从无梗五加(Acanthopanax sessiliflorus(Rupr.et Maxim.)Seem.)果70%乙醇提取物中分离鉴定了12个化合物。经波谱鉴定为东莨菪内酯(1),原儿茶酸甲酯(2),槲皮素(3),无梗五加苷B(4),金丝桃苷(5),(-)-pinoresinol-4,4′-di-O-β-D-glucopyranoside(6),chiisanoside(7),22α-hydroxychiisanoside(8),niduloic acid(9),胡萝卜苷(10),东莨菪苷(11)和无梗五加苷D(12)。其中化合物9为新天然产物,化合物1,2,6和11是首次从五加科植物中分离得到,化合物3是首次从五加属植物中分离得到。Twelve compounds were isolated from the 70% ethanol extract of the fruit of Acanthopartax sessiliflorus （ Rupr. et Maxim. ） Seem. ,which was fractionated on a macroporous resin column by 60% and 30% ethanol. They were identified as scopoletin （ 1 ）, protocatechuic acid methyl ester （ 2 ）, quercetin （3）, acanthoside B （4）, hyperin （ 5 ）, （-） -pinoresinol-4,4′-di-O-β-D-glucopyranoside （6）, chiisanoside （ 7 ）, 22α-hydroxychiisanoside （ 8 ）, niduloic acid （ 9 ）, daueosterol （10）,scopolin （11）,and acanthoside D （12）,by analysis of their spectroscopic data and by comparison with those reported on the literature. Compound 9 was a new natural product. 1,2,6 and 11 were isolated from Araliaceae for the first time and 3 was obtained from Acanthopanax genus for the first time.

关 键 词：五加属 元梗五加 niduloic ACID 东莨菪内酯 东莨菪苷 原儿茶酸甲酯 (-)-pinoresinol-4 4′-di-O-β-D- GLUCOPYRANOSIDE 槲皮素 

分 类 号：R284.1[医药卫生—中药学] Q946.91[医药卫生—中医学]