GLUCOPYRANOSIDE

作品数:23被引量:148H指数:8
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相关领域:医药卫生生物学更多>>
相关作者:冯卫生郑晓珂杨春娟熊志立于凯更多>>
相关机构:河南中医药大学北京大学沈阳药科大学中国中医科学院更多>>
相关期刊:《天然产物研究与开发》《Chemical Research in Chinese Universities》《Journal of Hainan Medical University》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金:国家自然科学基金“重大新药创制”科技重大专项博士科研启动基金国家高技术研究发展计划更多>>
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怀中1号地黄中2-phenylethyl-beta-glucopyranoside通过调节PI3K/Akt/mTOR/HIF-1α通路对低氧性肺动脉高压的影响
《中国中药杂志》2024年第14期3857-3867,共11页曾梦楠 张宇涵 郭彭莉 张梓玉 刘晏灵 王茹 铁玘美 王媛媛 常方卓 冯卫生 郑晓珂 
国家自然科学基金项目(32200322);国家重点研发计划项目(2019YFC1708802,2017YFC1702800);中央高校基本科研业务费项目(21622314)。
研究怀中1号地黄中2-phenylethyl-beta-glucopyranoside(Phe)对低氧诱导肺动脉高压小鼠的保护作用及其机制,为临床治疗肺动脉高压提供理论依据。首先将雄性C57BL/6N小鼠随机分为正常组,模型组,阳性药波生坦组(100 mg·kg^(-1)),Phe低、...
关键词:肺动脉高压 怀中1号地黄 2-phenylethyl-beta-glucopyranoside 缺氧 PI3K/Akt/mTOR/HIF-1α信号通路 
Mechanism of stilbene glycosides on apoptosis of SH-SY5Y cells via regulating PI3K/AKT signaling pathway
《Journal of Hainan Medical University》2024年第1期8-14,共7页KANG Bi-qian LI Yue HE Xiao-xuan XIAO Zhen HU Rui LUO Chen-liang QIAO Ming-yu WU Gui-you LI Zhen-zhong ZHU Xiao-ying HUANG Zhong-shi 
National Natural Science Foundation of China(No.81860709);Baise City Science and Technology Plan Project(No.Encyclopedia 20224139,Encyclopedia 20211807);2023 Youjiang Ethnic Medical College Graduate Innovation Program Project(No.YXCXJH2023013)。
Objective:To investigate the effects of stilbene glycoside(TSG)on okadaic acid-induced apoptosis in human neuroblastoma cells(SH-SY5Y)via the PI3K/AKT pathway.Methods:The optimal concentration of OA was screened by CC...
关键词:2 3 5 4'-tetrahydroxystilbene 2-O-glucopyranoside Alzheimer disease LY294002 Phosphatidylinositol 3-kinase(PI3K)/protein kinase B(AKT) Cell proliferation APOPTOSIS 
光皮木瓜中酚性成分研究被引量:8
《中国药学杂志》2020年第20期1666-1672,共7页石静亚 张志广 李孟 张靖柯 吕锦锦 郑晓珂 冯卫生 
中央引导地方科技发展专项项目资助(豫财科[2016]149号);河南中医药大学2018年度博士科研基金项目资助(BSJJ2018-08)。
目的研究光皮木瓜[Chaenomeles sinensis(Thouin)Koehne]化学成分,为药理活性筛选奠定基础。方法采用大孔吸附树脂Daion HP-20、Toyopearl HW-40、ODS中压制备和Sephadex LH-20柱色谱并结合半制备液相等传统的分离手段,对光皮木瓜的体...
关键词:光皮木瓜  苷类 6-O-(E)-feruloyl-β(α)-glucopyranoside 2 4 6-三羟基苯乙酮-2-O-吡喃葡萄糖苷 
New coumarin glucopyranosides from roots of Angelica dahurica被引量:3
《Chinese Herbal Medicines》2018年第1期103-106,共4页Ai-hong Zhao Xiu-wei Yang 
The National Natural Science Foundation of China (81473321);Beijing Municipal Natural Science Foundation (7152086);the National Key Technology R & D Program of China (2011BAI07B08;2012BAI29B02)
Objective: To investigate the chemical constituents from the roots of Angelica dahurica.Methods: The chemical constituents were isolated and purified by AB-8 macroporous adsorption resin and Sephadex LH-20 column as...
关键词:angedahuricoside A angedahuricoside B Angelica dahurica Benth. et Hook. f. ex Franch. et Sav coumarin glucopyranoside xanthoarnol-3-O-β-d-glucopyranoside 
Wound healing activity of Delonix elata stem bark extract and its isolated constituent quercetin-3-rhamnopyranosyl-(1-6) glucopyranoside in rats被引量:1
《Journal of Pharmaceutical Analysis》2016年第6期389-395,共7页Pradeepa Krishnappa Krishna Venkatarangaiah Venkatesh Santosh Kumar Shimoga Rajanna Rebijith Kayattukandy Balan 
partially supported by the Department of Biotechnology,New Delhi,India(Grant no.BT/PR11505/SPD/24/337/2008;BT/PR9128/INF/22/190/2013)
Delonix elata L.is a Ceasalpinaceae species and is traditionally used in India for treatment of skin diseases,liver diseases and rheumatic problems.However,systematic evaluation of its wound healing activity is lackin...
关键词:Delonix elata Quercetin-3-rhamnopyranosyl-(1-6) GLUCOPYRANOSIDE (QRPG) Wound HEALING HYDROXYPROLINE Tensile strength 
A colorimetric method for α-glucosidase activity assay and its inhibitor screening based on aggregation of gold nanoparticles induced by specific recognition between phenylenediboronic acid and 4-aminophenyl-α-D- glucopyranoside被引量:2
《Nano Research》2015年第3期920-930,共11页Juan Zhang Ying Liu Jun Lv Genxi Li 
A colorimetric method has been established for a-glucosidase activity assay and its inhibitor screening. The method is based on the specific recognition between 1,4-phenylenediboronic acid (PDBA) and 4-aminophenyl-a...
关键词:Α-GLUCOSIDASE inhibitor screening 1 4-phenylenediboronicacid gold nanoparticles 
披针叶茴香果实的化学成分研究被引量:8
《中国药学杂志》2014年第8期636-639,共4页李慧娟 王丽霞 刘孟奇 张雁冰 毕跃峰 柳继锋 
国家自然科学基金面上项目(81172961);中国科学院昆明植物研究所开放课题(P2009-KF10)
目的研究八角科(Illiciaceae)植物披针叶茴香(Illicium lanceolatum)果实的化学成分。方法应用硅胶、Sephadex LH-20、MCI等各种色谱技术进行分离纯化,根据化合物的理化常数和波谱数据鉴定其结构。结果从披针叶茴香果实的体积分数9...
关键词:八角属 披针叶茴香 2 4-dihydroxy—allylbenzene-2-O-β-D—glucopyranoside 芦丁 异鼠李素-3-O-β-D-芸香糖苷 6-deoxy-1-hydroxy neoanisatin 
红花水提取物的化学成分研究被引量:14
《中国药学杂志》2014年第6期455-458,共4页赫军 陈钟 杨桠楠 姜建双 冯子明 张培成 
"重大新药创制"科技重大专项(2012ZX09301002-001003)
目的对红花水提取物中的化学成分进行研究。方法通过大孔吸附树脂、Sephadex LH-20、反相HPLC等多种色谱进行分离纯化,根据理化性质和波谱数据进行鉴定。结果从红花水提物中分离得到了12个化合物,分别为(2E,8E)-12R—tetradeeadien...
关键词:红花 水提物 (2E 8E)-12R-tetradecadiene-4 6-diyne-1 12 14-triol (8Z)-decaene-4 6-diyn-1-O-β-D—glucopyranoside (8E)一decaene-4 6-diyn一1—0够一D—glucopyranoside 结构鉴定 
Bioguided Fractionation and Purification of Natural Bioactives Obtained from<i>Alpinia conchigera</i>Water Extract with Melanin Inhibition Activity
《Journal of Biomaterials and Nanobiotechnology》2013年第3期265-272,共8页Zanariah Binti Ujang Thavamanithevi Subramaniam Mazita Md Diah Harmayumi Binti Wahid Badariah Binti Abdullah Ahmad Hazri Bin Abd Rashid David Appleton 
Crude extracts of Alpinia conchigera a species from the Malaysian Ginger (Zingiberaceae) family and its fractions obtained from various extraction methods were assayed for melanogenesis inhibition activity and cell vi...
关键词:ALPINIA Conchigera Preparatory HPLC FRACTIONATION Chavicol GLUCOPYRANOSIDE Trans Cinnamaldehyde Anti-Melanogenesis ACTIVITY 
HPLC同时测定决明子中4种主要成分的含量被引量:17
《中国中药杂志》2011年第10期1327-1329,共3页苏会娟 王祝举 唐力英 
目的:建立HPLC同时测定决明子药材中蒽醌类和萘并吡喃酮类4种主要成分含量的方法,为决明子药材的质量控制提供依据。方法:采用Kromasil 100-5 C18色谱柱(4.6 mm×250 mm,5μm),流动相水-乙腈-四氢呋喃-冰醋酸(100∶23∶5∶1)等度...
关键词:高效液相色谱法 决明子 红链霉素龙胆二糖苷 aurantio—obtusin-6-O-β-D—glucopyranoside 决明子苷 决明子苷 B 含量测定 
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